ID   A0A3Q3MVC1_9TELE        Unreviewed;       498 AA.
AC   A0A3Q3MVC1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Paired box 2a {ECO:0000313|Ensembl:ENSMAMP00000031713.2};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000031713.2, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000031713.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   AlphaFoldDB; A0A3Q3MVC1; -.
DR   Ensembl; ENSMAMT00000032544.2; ENSMAMP00000031713.2; ENSMAMG00000021351.2.
DR   GeneTree; ENSGT00940000157412; -.
DR   InParanoid; A0A3Q3MVC1; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:Ensembl.
DR   GO; GO:0034672; P:anterior/posterior pattern specification involved in pronephros development; IEA:Ensembl.
DR   GO; GO:0001708; P:cell fate specification; IEA:Ensembl.
DR   GO; GO:0021588; P:cerebellum formation; IEA:Ensembl.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0061386; P:closure of optic fissure; IEA:Ensembl.
DR   GO; GO:0009880; P:embryonic pattern specification; IEA:Ensembl.
DR   GO; GO:0021703; P:locus ceruleus development; IEA:Ensembl.
DR   GO; GO:0030901; P:midbrain development; IEA:Ensembl.
DR   GO; GO:0030917; P:midbrain-hindbrain boundary development; IEA:Ensembl.
DR   GO; GO:0043049; P:otic placode formation; IEA:Ensembl.
DR   GO; GO:0007422; P:peripheral nervous system development; IEA:Ensembl.
DR   GO; GO:0035775; P:pronephric glomerulus morphogenesis; IEA:Ensembl.
DR   GO; GO:0072114; P:pronephros morphogenesis; IEA:Ensembl.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0030878; P:thyroid gland development; IEA:Ensembl.
DR   GO; GO:0060118; P:vestibular receptor cell development; IEA:Ensembl.
DR   CDD; cd00131; PAX; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR   InterPro; IPR001523; Paired_dom.
DR   InterPro; IPR022130; Pax2_C.
DR   InterPro; IPR043565; PAX_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR45636:SF45; PAIRED BOX PROTEIN PAX-2A; 1.
DR   PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR   Pfam; PF00292; PAX; 1.
DR   Pfam; PF12403; Pax2_C; 2.
DR   PRINTS; PR00027; PAIREDBOX.
DR   SMART; SM00351; PAX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00034; PAIRED_1; 1.
DR   PROSITE; PS51057; PAIRED_2; 1.
PE   4: Predicted;
KW   Paired box {ECO:0000256|ARBA:ARBA00022724};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          28..154
FT                   /note="Paired"
FT                   /evidence="ECO:0000259|PROSITE:PS51057"
FT   REGION          155..236
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..198
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..222
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  53220 MW;  0B3E8B2B6F299D19 CRC64;
     MNPPKDQPCP LQVCNVMLPC AAVVSHAGHG GVNQLGGVFV NGRPLPDVVR QRIVELAHQG
     VRPCDISRQL RVSHGCVSKI LGRYYETGSI KPGVIGGSKP KVATPKVVDK IAEYKRQNPT
     MFAWEIRDRL LAEGVCDNDT VPSVSSINRI IRTKVQQQFH PSPDGSVTPL STPGHTIVPS
     TASPPVTSAS NNPVGSYSIN GILGIPRSNG EKRKRDDDGS DGSGPGSDSQ GSVESLRKHL
     RADAFTQQQL EALDRVFERP SYPDVFSTSE HIKPEQANEY SLPSLNAGLE DVKPSLSTSA
     SSDLASSVSQ SYSVVTDSHP SYPPSMCLKR EPHEASFAPF TPCSVGDSAL ADILPHQCSL
     SVDASTPSYP AHARGSCYSQ YASQPFIAGR DMASTTLPGY PPHVPPTGQG SYPTSTLAGM
     VPGSPVDKHC FCSSPRLPGH PGLQRGDFSG NPYSHPQYTT YNEAWRFSNP ALLSSPYYYS
     AASRGSAPPT AATAYDRH
//