ID A0A3Q3N1M7_9TELE Unreviewed; 580 AA.
AC A0A3Q3N1M7;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Cationic amino acid transporter 2 family protein {ECO:0000313|Ensembl:ENSMAMP00000026164.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000026164.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000026164.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q3N1M7; -.
DR STRING; 205130.ENSMAMP00000026164; -.
DR Ensembl; ENSMAMT00000026837.2; ENSMAMP00000026164.2; ENSMAMG00000017561.2.
DR GeneTree; ENSGT00940000164978; -.
DR InParanoid; A0A3Q3N1M7; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR029485; CAT_C.
DR PANTHER; PTHR43243:SF19; AA_PERMEASE_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43243; INNER MEMBRANE TRANSPORTER YGJI-RELATED; 1.
DR Pfam; PF00324; AA_permease; 1.
DR Pfam; PF13906; AA_permease_C; 1.
DR PIRSF; PIRSF006060; AA_transporter; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 172..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..293
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 360..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..405
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 469..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 38..498
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 503..545
FT /note="Cationic amino acid transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13906"
SQ SEQUENCE 580 AA; 63329 MW; 5556A348FE0F933C CRC64;
MCGAKILLVL QSLSRLKPLE PEGEVSSFQR CLTTLDLVAL GVGSTLGAGV YVLSGEVARD
VAGPSIIISF LIAAVTSIFS GLCYAEFGAR VPRTGSAYLY CYVTVGEIWA FITGWNLLLS
YIMVTSSVAR AWSGNFDFLI SDVIANSLGK QAAMDLPGLA PYPDFSATLN NILTTVNILV
LLFVILSGFI KGDINNWCIS EDSLQYRNNT LLNETIRYGS GGFFPFGFEG TLAGAATCFN
AFVGFDHIAT TGEEVQNPQK SIPLSIVVCL LICFLAYFGV SAALTLMMPY YLLSVQSPLS
AAFAYIGWDA ANYAVAVGSL CALSTSLLGV MFPMPRVIFA MARDGLLFRP LSKTSDRQSP
VIATLTSGVV AAVMALLFDM KALIDMISIG ILFAYALVAI CILILRYQAD LSDDSSFSKE
PFSFSGVLYP PSQATIRTSK NVSVLTVFVS KSITLSLCIS RAVDSLQALE WWILLCVSVI
VLMLVLIILI IWRQPRSKTK AVFMVPFVPL LPIVSIFINV YLMVQLGSHT WIRYAVWMAV
GIKNYQSCEH DQRSCNFSFN RCNHLLWLWR PSQCTETKAS
//
