ID A0A3Q3N281_9TELE Unreviewed; 1103 AA.
AC A0A3Q3N281;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=MLLT10 histone lysine methyltransferase DOT1L cofactor {ECO:0000313|Ensembl:ENSMAMP00000034068.2};
GN Name=MLLT10 {ECO:0000313|Ensembl:ENSMAMP00000034068.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000034068.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000034068.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3N281; -.
DR STRING; 205130.ENSMAMP00000034068; -.
DR Ensembl; ENSMAMT00000034935.2; ENSMAMP00000034068.2; ENSMAMG00000022904.2.
DR GeneTree; ENSGT00940000157711; -.
DR InParanoid; A0A3Q3N281; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0060070; P:canonical Wnt signaling pathway; IEA:Ensembl.
DR GO; GO:0060729; P:intestinal epithelial structure maintenance; IEA:Ensembl.
DR CDD; cd20901; CC_AF10; 1.
DR CDD; cd15708; ePHD_AF10; 1.
DR CDD; cd15574; PHD_AF10_AF17; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR049773; AF10-like_CC.
DR InterPro; IPR049781; AF10/AF17_PHD.
DR InterPro; IPR049775; AF10_ePHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF93; PROTEIN AF-10; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 5..57
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 62..181
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 117..180
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 187..271
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 674..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 865..906
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1076..1103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 805..839
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 245..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..354
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..544
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 569..618
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 680..716
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 717..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1103 AA; 114428 MW; B2BF815F2651E56A CRC64;
MKEMIGGCCV CSDERGWAEN PLVYCDGHGC NVAVHQACYG IVQVPTGPWF CRKCESQERA
ARVRCELCPH KDGALKRTDN GGWAHVVCAL YIPEVEFANV STMEPIVLQS VPHERYNKTC
YICEDQGRES KAASGACMTC NKHGCRQAFH VTCAQFAGLL CEEQGSDADN VKYCGYCKYH
HSKLRRSRGR GSRSQSLSDS TSQCMDRPPD KDKKKHKERD RHKPKHKKSS MDMSPSLVLP
NIMVPDKTYN SSNSGGGIIS LPPSTQKRLD ENTGRFTNAN FQEVSSTHSS GSCKDVLAAD
TGKSASEVKN KKNSSGSHAV GQRGGRKSLT SSGKPLPSSV VTMATSSTSA SASTGPFHQG
LLLTSASKTP SASSSSDFLS FSDSSLRPGG GTTFSSPPSF SSCLVKPSSE GGASEGTSTL
FGSLMSATTG SAVGGKLYEN SHSHTASEMT SLGGSAGYKR PQSSSSGPGI SAAVAAGGDD
GVKKKKKGNW RNRFGPCFTT DVKPSEPAPS LTLPPSSTAS TTSSTASPSS SSSSTFSSRP
GLVSSSGLGV GGAGERGLGV MGVSGGMQKS PSLLRNGSLQ NNSGPTSTVP GVFSGADGLS
SGTGTVSSSE LSQQQQPMPS LAPPSPFTAT APLTSTASTH VSGLPGSIFN LAPSHMFGNR
LNPNSAMAAL IAQSEASPAV QRGREKDGEG EDKEREQDLE EPSVSPPRDK HIRNINQDVG
DGSSSVGAQG FSIRASPKTT PRSPIGGLQI RYDSSGSLPR LGLLGAGGGG VETLPPMATS
IEQLLERQWN EGQSFLLQQG AHGDVVGMLK SLHQLQEENR RLEEQIKTLT MKKERLQLLS
AQLSVPFTPT TASSDVKGAQ LGATDSSLPA AAQDSMSCGG HSSSGSTSSL STPPSVSQSP
PQLNGVAAVG TTPAGLGGVA GLMGALGAGS TLGMGGIGGA LNGVIQTPTG TASPHTHTTG
AATGVTLPVN NSSATSKNSA ARLGLLSGQH RLLLQQHQLQ QLLSSQPSPE QQQVLFYQLM
QQQQDLQQLQ SLSSSAQIPS MPLSSSQLPI NSLLPGTQSQ GQSTITTNPF LALQHPHTDA
HASGSQKPRI TEKAVGVTGQ EKT
//
