ID   A0A3Q3N510_9LABR        Unreviewed;       318 AA.
AC   A0A3Q3N510;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=NF-kappa-B inhibitor alpha {ECO:0000256|ARBA:ARBA00041123};
DE   AltName: Full=I-kappa-B-alpha {ECO:0000256|ARBA:ARBA00041987};
OS   Labrus bergylta (ballan wrasse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Labriformes; Labridae; Labrus.
OX   NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000028970.1, ECO:0000313|Proteomes:UP000261660};
RN   [1] {ECO:0000313|Ensembl:ENSLBEP00000028970.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NF-kappa-B inhibitor family.
CC       {ECO:0000256|ARBA:ARBA00038439}.
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DR   AlphaFoldDB; A0A3Q3N510; -.
DR   STRING; 56723.ENSLBEP00000028970; -.
DR   Ensembl; ENSLBET00000030337.1; ENSLBEP00000028970.1; ENSLBEG00000021949.1.
DR   GeneTree; ENSGT00940000163080; -.
DR   InParanoid; A0A3Q3N510; -.
DR   OrthoDB; 621606at2759; -.
DR   Proteomes; UP000261660; Unplaced.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR46680; NF-KAPPA-B INHIBITOR ALPHA; 1.
DR   PANTHER; PTHR46680:SF1; NF-KAPPA-B INHIBITOR ALPHA; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 6.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 3.
DR   PROSITE; PS50088; ANK_REPEAT; 3.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW   ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          118..150
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          190..222
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          224..256
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          280..318
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..310
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   318 AA;  35744 MW;  B31A275B9A338BAF CRC64;
     MDLHRTSILN QMDYSRDSKE GKPVQSMEER LDSGLDSLKE EEYQAVAAEI RRLQVDCEPP
     KHQQPPAVTG ELQAWKTQIT EDGDTLLHLA IIHEAKDYIR KMIDLSKNTD FLNTQNDQRQ
     TPLHLAVITN QADVCERLLV SGCDPTLVDD SGDTPLHIAC RHGNLLCFSV ITQNCQTEHL
     HKVMAACNYH GQNCLHLVSV QGFLSLVENM VDLGADIDAK EQRNGRGALH LAVDQQNLSL
     VKLLLKKGAD PNLLTSGGHT PYHLTYGRDN DDIRKELFSL TKPDLRELPD SESDDSEAEE
     DEESDDEVSY DDIQWNGH
//