ID A0A3Q3N5E2_9TELE Unreviewed; 465 AA.
AC A0A3Q3N5E2;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Nucleoporin 50 {ECO:0000313|Ensembl:ENSMAMP00000030636.1};
GN Name=NUP50 {ECO:0000313|Ensembl:ENSMAMP00000030636.1};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000030636.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000030636.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|ARBA:ARBA00004567}.
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DR AlphaFoldDB; A0A3Q3N5E2; -.
DR STRING; 205130.ENSMAMP00000030636; -.
DR Ensembl; ENSMAMT00000031435.2; ENSMAMP00000030636.1; ENSMAMG00000020659.2.
DR GeneTree; ENSGT00440000035348; -.
DR InParanoid; A0A3Q3N5E2; -.
DR OrthoDB; 4273059at2759; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0046907; P:intracellular transport; IEA:InterPro.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd13170; RanBD_NUP50; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR015007; NUP2/50/61.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR000156; Ran_bind_dom.
DR InterPro; IPR045255; RanBP1-like.
DR PANTHER; PTHR23138:SF141; NUCLEAR PORE COMPLEX PROTEIN NUP50; 1.
DR PANTHER; PTHR23138; RAN BINDING PROTEIN; 1.
DR Pfam; PF08911; NUP50; 1.
DR Pfam; PF00638; Ran_BP1; 1.
DR SMART; SM00160; RanBD; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50196; RANBD1; 1.
PE 4: Predicted;
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|ARBA:ARBA00023132};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00023132};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transport {ECO:0000256|ARBA:ARBA00022816}.
FT DOMAIN 351..465
FT /note="RanBD1"
FT /evidence="ECO:0000259|PROSITE:PS50196"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 113..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 204..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 291..351
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 291..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 465 AA; 48615 MW; FFD1EA1C5DEF4468 CRC64;
MAKRIADKEL TDRNWDQEDE GEEAGTFSVA SEDVLKNRAI KKAKRRNVGS EGESGGAFKG
FKGFSLTTGG GSIPAGFSGF GNGGGFKGLG GLTDGNSITP SFGGFSSPVT SSAAPGLMFN
GPTSTKPTAD VSTKQTNGSA PSPTQSSGSS SSSNKEYSRQ LTALNCSVRD WITKHVNDNP
LCDLNPIFRD YERHLASIER QYGAGATAPA DGSLEEKKKG GMLPTTATPP PSSSSSSSSS
AAPAPSPALF SFGKNTTENS AAASIPAGVT FNFGQKVDSS VLGSLGSKTT TPSFSFSSSS
STSSGQTSLF GAPGSAQLSF SGTKGEAAQP ADENGDEESE EPPKPEVKEV KEDDAFYSKK
CKLFYKKDSE FKDKGVGTLH LKQTEEGKTQ MIIRADTNLG NILLNIIVQA SMPCSRVGKN
NVMVICVPNP PVDDKNPSTP VPLLIRVKTS EDADELHKIL EEKKG
//
