ID A0A3Q3N909_9TELE Unreviewed; 410 AA.
AC A0A3Q3N909;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Potassium channel, subfamily K, member 12 {ECO:0000313|Ensembl:ENSMAMP00000032056.1};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000032056.1, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000032056.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the two pore domain potassium channel (TC
CC 1.A.1.8) family. {ECO:0000256|ARBA:ARBA00006666,
CC ECO:0000256|RuleBase:RU003857}.
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DR AlphaFoldDB; A0A3Q3N909; -.
DR STRING; 205130.ENSMAMP00000032056; -.
DR Ensembl; ENSMAMT00000032891.2; ENSMAMP00000032056.1; ENSMAMG00000021566.2.
DR GeneTree; ENSGT00940000161424; -.
DR InParanoid; A0A3Q3N909; -.
DR OrthoDB; 600333at2759; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005267; F:potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR003280; 2pore_dom_K_chnl.
DR InterPro; IPR005410; 2pore_dom_K_chnl_THIK.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11003:SF11; POTASSIUM CHANNEL SUBFAMILY K MEMBER 12; 1.
DR PANTHER; PTHR11003; POTASSIUM CHANNEL, SUBFAMILY K; 1.
DR Pfam; PF07885; Ion_trans_2; 2.
DR PRINTS; PR01333; 2POREKCHANEL.
DR PRINTS; PR01588; THIKCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 3: Inferred from homology;
KW Ion channel {ECO:0000256|RuleBase:RU003857};
KW Ion transport {ECO:0000256|RuleBase:RU003857};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003857};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU003857};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 22..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 94..151
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 206..282
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 313..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 410 AA; 45370 MW; 95781E41165C6782 CRC64;
MMPGQRLHGC RSLHFNEDNG RFVLLAILIL LYLLCGAAVF SAIERPSELR AHGRWNGTLH
NFSETFNISL QDLNSFLREY EAAIAAGIRA DALRPRWDFT GAFYFVGTVV STIGFGMTTP
VTVAGKVFLI FYGLLGCAAT ILFFNLFLER IITLLAVVMK AVRERRIRNS GLLPPGIRHD
FSAYSLPGWK PSVYHVMLIL GLSAITISCC ASAMYTPVEG WAYLDSLYFC FVTFSTIGFG
DFVSSQNAAY EYQSLYRVAN FLFMLMGVCC IYSLFNVISI VIKQVLNWML EKMSCLFCQR
CNKANAFLGR RNAIRPGSKG RQGRFGQPPD SDGPCDSDTE GRRLSGEMIS MKDLAASNKV
SLAIMQKQLS ESANGYPRTV CSSSRHNGFS GGVGALGIMN NRLAETSNSR
//
