ID A0A3Q3NA02_9LABR Unreviewed; 699 AA.
AC A0A3Q3NA02;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Scm polycomb group protein like 2 {ECO:0000313|Ensembl:ENSLBEP00000030875.1};
GN Name=SCML2 {ECO:0000313|Ensembl:ENSLBEP00000030875.1};
OS Labrus bergylta (ballan wrasse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Labriformes; Labridae; Labrus.
OX NCBI_TaxID=56723 {ECO:0000313|Ensembl:ENSLBEP00000030875.1, ECO:0000313|Proteomes:UP000261660};
RN [1] {ECO:0000313|Ensembl:ENSLBEP00000030875.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SCM family. {ECO:0000256|ARBA:ARBA00008469}.
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DR AlphaFoldDB; A0A3Q3NA02; -.
DR STRING; 56723.ENSLBEP00000030875; -.
DR Ensembl; ENSLBET00000032292.1; ENSLBEP00000030875.1; ENSLBEG00000023322.1.
DR GeneTree; ENSGT00940000159407; -.
DR InParanoid; A0A3Q3NA02; -.
DR OrthoDB; 2908161at2759; -.
DR Proteomes; UP000261660; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20092; MBT_dScm-like_rpt2; 1.
DR CDD; cd09578; SAM_Scm; 1.
DR Gene3D; 2.30.30.140; -; 2.
DR Gene3D; 3.90.1150.190; SLED domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR047531; SAM_Scm-like.
DR InterPro; IPR033763; SCML2_RBR.
DR InterPro; IPR021987; SLED.
DR InterPro; IPR038348; SLED_sf.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR PANTHER; PTHR12247:SF84; SEX COMB ON MIDLEG-LIKE PROTEIN 2; 1.
DR Pfam; PF02820; MBT; 2.
DR Pfam; PF17208; RBR; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF12140; SLED; 1.
DR SMART; SM00561; MBT; 2.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 2.
DR PROSITE; PS51079; MBT; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261660};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT REPEAT 35..133
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 141..242
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 628..697
FT /note="SAM"
FT /evidence="ECO:0000259|SMART:SM00454"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 254..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..359
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 497..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 523..545
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 546..629
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 76951 MW; 799A21A855CEB4CF CRC64;
MGKTPLKDQK DGKKDKLGRT VPPAGTTPAA TKDSFSWEEY LKETSAMPAP PSCFRQARIP
PSNDFKVGMK LEAHDPRNST SVCIATVMGL TGVRLRLRLD GSDNSNDFWR LVDSSDIQPI
GTCEKNGDML QPPLGFRMNA SSWPMFLLRT LNGAEMAPAT AFKKEPLRPT QNHFKPGMKL
EAVDKKNPYL ICPATIGEVK GDEVFIMFDG WRGAFDYWCK YDSRDIFPVG WCSLTKHSLQ
PPGNSVTLPK SLQILPASPS KPNRRAMQSP YRLPNPLPPL PVRKGVRGRR PKSETIALLK
AVAEAAAAHN GTVPENTQLV PRPHKKRGPK PGSKRKPKIL QSPAQLPSIQ VPQESSPSHN
SVVSTVCVYV NKHGNCGSHL DRKQMQRLPD HFGPGPVNAV LQKVVQSCID CAYQPKVLLS
ALQTHSGGGE VVRVRTDGGV CMVKLPAASS ASFVLRFLET MCRHLQCDNL FSSQPFSHYT
AYDRTKSVKE EVLDAPSLAR GSKRSLSGIS PSYAAPLSPK HLRTEAHPSE AETLPHEENG
HIKEQRYMDS ASNSMTPRPQ TARSSSEYHS QTSSLYHAGN ATTMRRLSSN PGELSSTPPL
RRVEASSTTG PEALGSERES LQLPSKNPSS WSIEEVMQFV RDADPTALAP HAELFRKHEI
DGKALMLLRS DMIMKYMGLK LGPALKLCHH IDRLKQGKL
//
