ID   A0A3Q3NCR1_9TELE        Unreviewed;       998 AA.
AC   A0A3Q3NCR1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Exportin 1 (CRM1 homolog, yeast) a {ECO:0000313|Ensembl:ENSMAMP00000034287.2};
GN   Name=XPO1 {ECO:0000313|Ensembl:ENSMAMP00000034287.2};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000034287.2, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000034287.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   AlphaFoldDB; A0A3Q3NCR1; -.
DR   Ensembl; ENSMAMT00000035159.2; ENSMAMP00000034287.2; ENSMAMG00000023037.2.
DR   GeneTree; ENSGT00940000153408; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR041123; CRM1_repeat.
DR   InterPro; IPR041235; Exp1_repeat_2.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR045065; XPO1/5.
DR   InterPro; IPR014877; XPO1_C_dom.
DR   InterPro; IPR040485; XPO1_repeat_3.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF16; EXPORTIN-1; 1.
DR   Pfam; PF08767; CRM1_C; 1.
DR   Pfam; PF18777; CRM1_repeat; 1.
DR   Pfam; PF18784; CRM1_repeat_2; 1.
DR   Pfam; PF18787; CRM1_repeat_3; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SMART; SM01102; CRM1_C; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          636..954
FT                   /note="Exportin-1 C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM01102"
SQ   SEQUENCE   998 AA;  114594 MW;  901C3ED6DAF7DBD7 CRC64;
     YVQGHYLHYY ALQILEAVIK TRWKILPRNQ CEGIKKYVVG LIIKTSSDPA NMEKDGVYIS
     KLNMILVQIL KQEWPKHWPT FISDIVGASR TSESLCQNNM IILKLLSEEV FDFSSGQMTQ
     VKAKHLKDSM CNEFSQIFQL CQFVMENSQN APLVHATLET LLRFLNWIPL GYIFETKLIS
     TLVYKFLNVP MFRNVTLKCL TEIAGVSVSQ YEEQFVSLFT LTMCQLKQML PLNTNIRVAY
     SNGKDDEQNF IQNLSLFLCT FLKEHGQLVE KRPNLRETLM EALHYMLLVS EVEETEIFKI
     CLEYWNHLAA ELYRESPFST SSTPLLSDVP PRRHLYLPVL SQVRLLMVSR MAKPEEVLVV
     ENDQGEVVRE FMKDTDAINL YKNMRETLVY LTHLDYADTE RIMTEKLHNQ VNGTEWSWRN
     LNMLCWAIGS ISGAMHEEDE KRFLVTVIKD LLGLCEQKRG KDNKAIIASN IMYIVGQYPR
     FLRAHWKFLK TVVNKLFEFM HETHDGVQDM ACDTFIKIAQ KCRRHFVQVQ VGEVMPFIDE
     ILNNINTIIC DLQPQQVHTF YEAVGYMIGA QTDQAVQELL IEKYMLLPNQ VWDSIIQQAT
     KNVDILKDAE TVRQLGSILK TNVRACKAVG HPFVVQLGRI YLDMLNVYKC LSENISSAVQ
     TNGEMVTKQP LIRSMRTVKR ETLKLISGWV SRSNDPQMVA ENFVPPLLEA VLIDYQRNVP
     AAREPEVLST MATIVNKLGA HITGEIPKIF DAVFECTLNM INKDFEEFPE HRTHFFYLLQ
     AATSQCFPAF LSIAPAQFKL ILDSIIWAFK HTMRNVADTG LQILYTLLQN VSAEEAAAQS
     FYQTYFCDIL QHIFSVVTDT SHTAGLTMHA TILAYMFNLV EEGKVSVALS AASPISNQAY
     VQEYIANLLK TAFPHLQDAQ VKVFVTGLFS LNQDIPAFKE HLRDFLVQIK EFAGEDTTDL
     FLEEREAALR QAQEEKHKLQ MSVPGILNPH ELPEEMCD
//