ID A0A3Q3NE63_9TELE Unreviewed; 1055 AA.
AC A0A3Q3NE63;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=FERM domain containing 4Ba {ECO:0000313|Ensembl:ENSMAMP00000034857.2};
GN Name=FRMD4B {ECO:0000313|Ensembl:ENSMAMP00000034857.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000034857.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000034857.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3NE63; -.
DR STRING; 205130.ENSMAMP00000034857; -.
DR Ensembl; ENSMAMT00000035753.2; ENSMAMP00000034857.2; ENSMAMG00000023408.2.
DR GeneTree; ENSGT01020000230354; -.
DR InParanoid; A0A3Q3NE63; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR GO; GO:0090162; P:establishment of epithelial cell polarity; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13191; FERM_C_FRMD4A_FRMD4B; 1.
DR CDD; cd17200; FERM_F1_FRMD4B; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR021774; CUPID.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR047176; FRMD4A/B.
DR InterPro; IPR041785; FRMD4A/B_FERM_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR46079; FERM DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR46079:SF1; FERM DOMAIN-CONTAINING PROTEIN 4B; 1.
DR Pfam; PF11819; CUPID; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT DOMAIN 59..361
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 570..616
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 651..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 723..752
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 909..935
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 406..444
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 523..550
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 723..743
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1055 AA; 120452 MW; 8457B52669F1A2A1 CRC64;
MAVRIIRGME DLVASGSQLI WSLAHHTLRR WYNHGLMPCR RFLEAWFRIG KFYQMTEGRL
CQVQLLDGRN LELLVQPKLL SRELLDLVAS HFNLKEKEYF GLCFIDDTGQ NNWLQLDRKV
LDHDFSKTGG PLELKFLVRF YIEKITYLKE NKTVELFFLN AKSLVFNETI EVESANVFKL
AAFALQEAKG DYSSAETARS DLKELPVLPT RVLREHPSLN YCEDKVIEHY KKLKGLTRGQ
AIVQYLGLVE SQSTYGVHYY PVKDKQGIPW WLGVSYKGIG QYDLQDKLKP RKLFHWKQLE
NLYFREKKFA VEVNDPHRRA VTKRTFGQSG LVIHTWYASH SLIKTIWVMA ISQHQFYLDT
KETKSKMTMT RSSVDIAMDL TETYPQRISK DQLIMASNGS LISAGSADSE VNEEQKKEKI
AELKKKEKDL QDKLTQKLDE LKKICMREAE LTGRLPKEYP LATGEKAPQV RRRVGTAFKL
DDLFPYDEDP YLRNLESKFA LQQKIVEAAI KLASEGDLCK TVKKKRKNNF LDAKRMLEEI
EKEINTYRIK KGKKPTQRAS LILADDVNPS DLSSLSDSLT LDDDDEIGSQ RQRSRSVQYS
PRPHHAETLD IPYSKDRRVS ANDMHADSRL NSGQAHYSQS DALSSHSNNF KLASRQPRDA
RSMPPTPLLT RNAYSSTQLR SDDAPQHFRQ RSGSLESQSQ FLTETETPVA TFTFIPARRS
NSTEVLDDGS SYTSQSSVEY SIPGNHTHRH RIHGRHRKDL YANTGSMPNL AQPDGRCYQP
RARPTTTAYY VTGYPTYTEP ESYGSGAYMY DNEMEGHYNV QPSYYPTPTA YNSRMCSQYD
NDEIDGMSQN LYATLRPPRN RPPHGNEQVS KNVHKALVVE HLRDWYHRSA AQKQTPYNYD
YDYERGSQQS LGYQTMPPPY NNRNTSYSSA SSASSTANWH SHMSGGMLEY GMSMLAPQSY
TYSTAPYSHS THSRYGASQL LKGPWHSPDG LRRRAFYPAS CSSSASSSTS LPSSSFPSSS
YSPGFWVKQV ASSPAQPQSS RGHRLSKVPF AKGSS
//
