ID A0A3Q3NEM0_9TELE Unreviewed; 494 AA.
AC A0A3Q3NEM0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Target of myb1 like 2 membrane trafficking protein {ECO:0000313|Ensembl:ENSMAMP00000035032.2};
GN Name=TOM1L2 {ECO:0000313|Ensembl:ENSMAMP00000035032.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000035032.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000035032.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TOM1 family. {ECO:0000256|ARBA:ARBA00007708,
CC ECO:0000256|PIRNR:PIRNR036948}.
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DR AlphaFoldDB; A0A3Q3NEM0; -.
DR Ensembl; ENSMAMT00000035933.2; ENSMAMP00000035032.2; ENSMAMG00000023519.2.
DR GeneTree; ENSGT00940000156940; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR CDD; cd14238; GAT_TM1L2; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF31; TOM1-LIKE PROTEIN 2; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036948};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036948}.
FT DOMAIN 20..152
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 214..302
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 181..201
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 334..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 53581 MW; 9D9A66FA8E410F47 CRC64;
MEFLLGNPYS TPVGQCIERA TDGGLQNEDW ALNMEICDII NETDEGPKDA MRALKKRLSG
NKNYREVMLA LTVLETCVKN CGHRFHVHVA NRDFIDGVLV KIISPKANPP TIVQDKVLSL
IQAWADAFRS SPDLTGVVHI YEELKRKGIE FPMADLDALS PIHTPQRGTP EVDPAMLKYL
APASPATGTP NPAPNPASAT QMSHVSSPIT ATPEQIARLR SELDIVRGNI KVMSEMLTEM
VPGQEDASDL ELLQELNRTC RAMQQRVVEL ISRVSNEEVT EELLHVNDDL NNIFLRYERY
ERYRLGRAAQ NNGMLNESSE DNLIDLGPGS PAVVTPRITS SPPLHSTAGA TASSAHNPTT
ASLSTALAGL DVGSDSVSGT LSSLSGHNQD DFDMFAQTRS SSLAEQRKNV KYEDPQALSS
LASALDVRQQ NTGGKGDAAE EGVTSEEFDK FLEERAKAAD TLPSPPGANP AHPARAPSGS
HKKGERTEDA LFAL
//
