ID   A0A3Q3RFH5_9TELE        Unreviewed;       257 AA.
AC   A0A3Q3RFH5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Toll-interleukin 1 receptor (TIR) domain containing adaptor protein {ECO:0000313|Ensembl:ENSMAMP00000000640.1};
GN   Name=TIRAP {ECO:0000313|Ensembl:ENSMAMP00000000640.1};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000000640.1, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000000640.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3RFH5; -.
DR   Ensembl; ENSMAMT00000000654.2; ENSMAMP00000000640.1; ENSMAMG00000000461.2.
DR   GeneTree; ENSGT00510000048428; -.
DR   InParanoid; A0A3Q3RFH5; -.
DR   OrthoDB; 5392575at2759; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR017279; Tol-interleuk_rcpt_adapt_Tirap.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR22662; TIRAP; 1.
DR   PANTHER; PTHR22662:SF0; TOLL_INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT   DOMAIN          67..205
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   REGION          35..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          212..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        218..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   257 AA;  28709 MW;  5DBF286368B96683 CRC64;
     MHGWLQKLLK PRISLSTQQE HEAKVTRVSS LALSSFSSSS SSSSPGAVPS KPQQPQSALS
     SQQRYNLKYD LLVCHSSADN DIEVANHLVS FLEASPQSLR CFLWHRDVCP GGAFFTEFCQ
     AVQDSHLQAL LITPEFLQED TCKYMLHQTL AEGPMSNRLI PLVHNLAHSQ YPQELKFCIY
     INLSNNTNRG YNLINRTVLS YLEDLVKKEK TNNKDSCSKN SQKDGLMSNT NPAETSGPLE
     VLQKSNESLN DVCCGHH
//