ID   A0A3Q3RW83_9TELE        Unreviewed;       176 AA.
AC   A0A3Q3RW83;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Protein Dr1 {ECO:0000256|ARBA:ARBA00018742};
DE   AltName: Full=Down-regulator of transcription 1 {ECO:0000256|ARBA:ARBA00032651};
DE   AltName: Full=Negative cofactor 2-beta {ECO:0000256|ARBA:ARBA00030451};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000011705.1, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000011705.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NC2 beta/DR1 family.
CC       {ECO:0000256|ARBA:ARBA00009245}.
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DR   AlphaFoldDB; A0A3Q3RW83; -.
DR   Ensembl; ENSMAMT00000012019.2; ENSMAMP00000011705.1; ENSMAMG00000007916.2.
DR   GeneTree; ENSGT00550000075010; -.
DR   InParanoid; A0A3Q3RW83; -.
DR   OrthoDB; 297906at2759; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0017054; C:negative cofactor 2 complex; IEA:InterPro.
DR   GO; GO:0140223; F:general transcription initiation factor activity; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   InterPro; IPR003958; CBFA_NFYB_domain.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR042225; Ncb2.
DR   PANTHER; PTHR46138; PROTEIN DR1; 1.
DR   PANTHER; PTHR46138:SF1; PROTEIN DR1; 1.
DR   Pfam; PF00808; CBFD_NFYB_HMF; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT   DOMAIN          12..75
FT                   /note="Transcription factor CBF/NF-Y/archaeal histone"
FT                   /evidence="ECO:0000259|Pfam:PF00808"
FT   REGION          148..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        148..166
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   176 AA;  19464 MW;  DBAD37B36A09FA0F CRC64;
     MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI SSEANEICNK
     SDKKTISPEH VINALESLGF ASYITEVKDV LQECKTVALK RRKASSRLEN LGIPEEELLR
     QQQELFAKAR QQQAELAQQE WLQMQQAAQQ AQMAAASASA AQQAGSSQDE DEDDDM
//