ID   A0A3Q3RWA6_9TELE        Unreviewed;      1231 AA.
AC   A0A3Q3RWA6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Dynactin subunit 1 {ECO:0000256|ARBA:ARBA00016574};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000011765.1, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000011765.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00011010}.
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DR   AlphaFoldDB; A0A3Q3RWA6; -.
DR   Ensembl; ENSMAMT00000012080.2; ENSMAMP00000011765.1; ENSMAMG00000007880.2.
DR   GeneTree; ENSGT00940000155378; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
DR   GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR   InterPro; IPR036859; CAP-Gly_dom_sf.
DR   InterPro; IPR000938; CAP-Gly_domain.
DR   InterPro; IPR022157; Dynactin.
DR   PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR   PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR   Pfam; PF01302; CAP_GLY; 1.
DR   Pfam; PF12455; Dynactin; 1.
DR   SMART; SM01052; CAP_GLY; 1.
DR   SUPFAM; SSF74924; Cap-Gly domain; 1.
DR   PROSITE; PS00845; CAP_GLY_1; 1.
DR   PROSITE; PS50245; CAP_GLY_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Dynein {ECO:0000256|ARBA:ARBA00023017};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT   DOMAIN          34..76
FT                   /note="CAP-Gly"
FT                   /evidence="ECO:0000259|PROSITE:PS50245"
FT   REGION          84..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1077..1101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          913..1004
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1048..1075
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1138..1165
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        115..133
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1231 AA;  136496 MW;  D18B806FC9E81221 CRC64;
     MSSSGTTESS KPPKIGSIVE VTGKGQRGTV AYIGATLFAS GKWVGVILDE PKGKNDGTVQ
     GKRYFTCEEN HGIFVRQSQI QVVEEGSSAS SPDVPESGIA KMTKQKDIPE TPKTTKQASR
     ESLSSSLSGD VSEAGLSPHQ GALGAPVVPQ PSGSPAATAT PVPATPSKVE PVISKQEEES
     LRAQVKDLEE KLETLKMKRT EDKAKLKELE KHKIQLEQLQ EWKTKMQEQQ AELQKQLKEA
     KKEAREAQEA KDRYMEEMSD TADAIEMATL DKEMAEERAE SLQVEVDTLK EKVEELSMDL
     EILRHEISEK GSEGAASSYH VKQLEEQNGR LKEALVRMRD LSASEKQEHV KLQKQMEKKN
     TELESLRTQK EKLQEELTQA EATIDELKEQ VDAALGSEEM VETLTERNLD LEEKVRELRE
     TVTDLEAINE MNDELQENSR ETEMELREQV DLSAAKVREA EKRVEAAQET VADYQQTISK
     YRELTARLQE ANRELISQQN ANTEQGQQPP AELFDFKIKF AETKAYAKAI EMELRKMEVA
     QSNRQVSLLT SFMPDSFVRH GGDHDCILVL LLIPRLICKA ELISKQAQEK FDLNGNLVQG
     TGLRGPPGEQ RSFSSGLVYS LSLLQATLHK YEQALNTCSV EVFKRMGTLY SEMSFHERSL
     DYFIDLLHKD QLDETVQVEP LTKAIKYYQQ LYSVHLADHT EDCTVQLADH IKFTQSALDC
     MGVEVARLRA FLAPGQESSG LALLLKDLDT SCSDIRQFCK KIRRRMPGTD VVGVPAALNF
     GPQVSETLTE CRRQQTRVVA VLQEVAAAGA QMVAPLAEQE GLNALKLEDT ACKAVEQVYG
     SHGLNGPECL RQSCSSVIAT MNKMATAMQE GEYDADKPQG KTPPVEIRAA AVRAEMTDAE
     GLGVKLEDRE TVIKELKKSL KIKGEELSEA NVRLSLLEKK LDTSTKDADE RVEKIQTKLD
     ENLALLKKKE KEFEETMDAL QADIDQLEAE KAELKQRINN QSKMTIEGLR GTASSGIASI
     VHGSTGGMGP SMAGPLQVVD SPLLRQQIEA QRLGIKYLKN ENNRLKAEKM RAQLASLPPL
     CPPKLPRVTK ESSMPPEGLN TGIYRRTDQL LATLLKLSAE VKVVDITGKT AVSASAQLLE
     QTARLQNLSD ALSKLKREVA EHVVSNQPGA KASSDFATFP VSSFVKAKEE KQGGTMYIGR
     VSIPCARGQE QVHRLVLSQQ QLHQVHGLLM A
//