ID   A0A3Q3SR09_9TELE        Unreviewed;      1219 AA.
AC   A0A3Q3SR09;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   02-JUN-2021, sequence version 2.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Uncharacterized LOC113122983 {ECO:0000313|Ensembl:ENSMAMP00000029045.2};
OS   Mastacembelus armatus (zig-zag eel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX   NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000029045.2, ECO:0000313|Proteomes:UP000261640};
RN   [1] {ECO:0000313|Ensembl:ENSMAMP00000029045.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR   AlphaFoldDB; A0A3Q3SR09; -.
DR   STRING; 205130.ENSMAMP00000029045; -.
DR   Ensembl; ENSMAMT00000029794.2; ENSMAMP00000029045.2; ENSMAMG00000019548.2.
DR   GeneTree; ENSGT00940000164632; -.
DR   InParanoid; A0A3Q3SR09; -.
DR   Proteomes; UP000261640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR46006:SF5; DH DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46006; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50010; DH_2; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261640}.
FT   DOMAIN          821..1012
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   DOMAIN          1058..1195
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          242..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          292..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          681..776
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1099..1120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        292..323
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        326..362
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        404..420
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        421..481
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        681..709
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        720..737
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        740..764
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1219 AA;  134288 MW;  FEA4232DA3797D5F CRC64;
     MPDVKPPPPC DYPSTSSAVA SAGTPAGCAS PLSFIIDMEP CITNLPLSPN PLSSFSQHTP
     SVPHYPGLQG PPFPLMARCN SSTLLTNLGL RYCSNRQSPL GVGPGLEQAP GSCVHTGSNG
     SRPYRSMENL NWNAVADSGL CAFNAAPYRS VDSEFILRYT STSHWYDGAP NGSMLGAHGL
     VPSPERLAFY PRHGLPRKDL PLFPQLLFPG GIDEWDARRG LREKLRLQSA RSAVEPLKHL
     PLRPQVTPGA TPIEREGVHS TGAGSKPLCT MRITSPEEIK QEVLRRLQLR RQNSSPNLAV
     HSSQSSPKVV KTSYTTDNIA GKRNGADSIS EHRRPPVGRL HIPTFEEFKR MRQKDREIHR
     ESTAGPVASG KPEAFLGDAG VDEDKLPPSD LNGSQSSSRV GDGKQRGGFE EVKRDNSTGE
     ITDTSSEGLQ TTTSLEIFPS STTENNSTAD PTSSSSTSIT SSYSPIRTGP SPRSPLQPLA
     SSDQEKAVAA GGDVGSSRRR RSSLEPAGSI PFPPNRENWE RPSSCCPALL LEGADLSSYG
     AKIYKMKDGL IGSALDLIKK SCSAEISAEA PVRLSGDRGR VCDITAPSTD CQPSAVAMAT
     SATACRADAG DETPAGGGGR EEAGECHTGL GCRRSSSDAA YELAETVRAQ RECRLRPHYS
     DPMPADASKR KQLEMKIAAA ARLHGHRRDR DRDRDSAPAA IRGRSEPPGE ERQAGLGVTR
     SGQHRWSTIS SLSADSGVVG LSDEREEEDS EPRRYRRSRG AEVERVDSGI GPGLSRTWKR
     PSASLRAWES QRPCPDCGLR DGASKERGER MCERCSKLRT ERKEAILEFL NTESSYGEDL
     RIIKEEFYCP MQSAGLLTAE QLTVVFGNVQ ELIDVNDRFT EHLQDSIDQA FDQGDEDLLT
     VYIGEIFLEF VNMLPAFQTY CLQQSTSVNM LNTLEKEKEL LRIFLDVSQN DNTALRRMNL
     RSFLMAPLQR VTKYPLLLSR IIKVTPECHP DYSRLREAKS RVESHLEHIN MKTKQEGNGV
     TWSLRSFRRD SRKNREVINI EMREVSMKTV GWSRENTRFV MEGPLQLSQP ADGQWVKKGS
     KALKFQNVQS LLMVRTQRVG EAPGQGTDLG ARGEQGDGGG ESVRDGVLVL IKDKSSGKFT
     VLREPIRLGN CVVSTEPDCE DTFEVLDIRR ESFVFRASDK SRTQQWFHQI RRYARDLGTW
     RKRRNALPNI MINTNQTRS
//