ID A0A3Q3SY25_9TELE Unreviewed; 536 AA.
AC A0A3Q3SY25;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 02-JUN-2021, sequence version 2.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Solute carrier family 19 member 1 {ECO:0000313|Ensembl:ENSMAMP00000032620.2};
OS Mastacembelus armatus (zig-zag eel).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Anabantaria; Synbranchiformes; Mastacembelidae; Mastacembelus.
OX NCBI_TaxID=205130 {ECO:0000313|Ensembl:ENSMAMP00000032620.2, ECO:0000313|Proteomes:UP000261640};
RN [1] {ECO:0000313|Ensembl:ENSMAMP00000032620.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|PIRNR:PIRNR028739}; Multi-
CC pass membrane protein {ECO:0000256|PIRNR:PIRNR028739}.
CC -!- SIMILARITY: Belongs to the reduced folate carrier (RFC) transporter (TC
CC 2.A.48) family. {ECO:0000256|ARBA:ARBA00005773,
CC ECO:0000256|PIRNR:PIRNR028739}.
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DR AlphaFoldDB; A0A3Q3SY25; -.
DR STRING; 205130.ENSMAMP00000032620; -.
DR Ensembl; ENSMAMT00000033469.2; ENSMAMP00000032620.2; ENSMAMG00000021952.2.
DR GeneTree; ENSGT00950000183022; -.
DR InParanoid; A0A3Q3SY25; -.
DR Proteomes; UP000261640; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0090482; F:vitamin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002666; Folate_carrier.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00806; rfc; 1.
DR PANTHER; PTHR10686; FOLATE TRANSPORTER; 1.
DR PANTHER; PTHR10686:SF12; REDUCED FOLATE TRANSPORTER; 1.
DR Pfam; PF01770; Folate_carrier; 1.
DR PIRSF; PIRSF028739; Folate_carrier; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR028739, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|PIRNR:PIRNR028739}.
FT TRANSMEM 104..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 130..148
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 314..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 349..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 473..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 536 AA; 60007 MW; 8482A24BC3C013E1 CRC64;
MVAEVTAGSG DKLEEEKAMD LKVPVSENTE RHEDGDMAVC ASEAVTPSED PTEESREPIK
WEWAVIFLCF YGFMSSIKPG EPFITPYLLS PEKNFTREQV TNEITPVLTY SYMAVLVPAF
LLTDLLRYKP VLIIQGISQV VIWLILLLGT NLIEMQFMEF FYGITMACRV AYSSYIFSLV
SPVLYQRVAG YSRSSVLLGV FTSSVLGQLC ISLGNMRFYT LSAVSLGFVS FGLLLAMWLP
WPKRSMFFNR MKNQEQRELA ATGATKSELD QMNPKASRLP PPASTCSASC WKDSVLVQML
LEVRNLVRRP NLRLWSLWWV FNSTGYYLVL FYVHILWNKV TDNKTVYNGG VEAASTLLSA
ATSFMAGFVK IRWNVWSELV IGVITAVQAG LLLLMGTTGN IWVCYVAYIL FRGFYQFLVP
IATFQIASSL TKELCALVFG INTFLGTILK TIINLIFSDK RGLAMDVHSQ FKVYFIYFTL
LTVTYFACAA VVIYRHHRNQ PQGGGTASDP ELPAELSAAA LSSEDELLSN SKSAKV
//
