ID   A0A3Q3VKA9_MOLML        Unreviewed;       452 AA.
AC   A0A3Q3VKA9;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=SH2 domain-containing protein {ECO:0000259|PROSITE:PS50001};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000001456.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000001456.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3VKA9; -.
DR   Ensembl; ENSMMOT00000001485.1; ENSMMOP00000001456.1; ENSMMOG00000000411.1.
DR   OMA; DWLGIHN; -.
DR   Proteomes; UP000261620; Unplaced.
DR   CDD; cd09942; SH2_nSH2_p85_like; 1.
DR   Gene3D; 1.10.287.1490; -; 1.
DR   Gene3D; 3.30.505.10; SH2 domain; 2.
DR   InterPro; IPR032498; PI3K_P85_iSH2.
DR   InterPro; IPR035022; PI3kinase_P85_nSH2.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   PANTHER; PTHR10155; PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT; 1.
DR   PANTHER; PTHR10155:SF10; PI3K21B, ISOFORM B; 1.
DR   Pfam; PF16454; PI3K_P85_iSH2; 1.
DR   Pfam; PF00017; SH2; 2.
DR   PRINTS; PR00678; PI3KINASEP85.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 2.
DR   SUPFAM; SSF55550; SH2 domain; 2.
DR   PROSITE; PS50001; SH2; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN          49..144
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   DOMAIN          335..429
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
SQ   SEQUENCE   452 AA;  52909 MW;  14E45AA7C0020240 CRC64;
     MVYPPEGLFY IEMDQAPPAL PPRSSKPVSS NMNNNCLVPP VCSLQDAEWY WGDITRDEVN
     EKLRDKPDGS FMVRDASTKL QGDFTLTLRK EGHNKLIKIY HRDGKYGFSD PLTFTSVVEL
     IWYYQHHSLV EYNATLDLML THPVSRFQRV KEDSVDVAGR KLKEVHSQYQ EKTKEFDRLY
     EAFTKTSQEI QMKRTAIEAF NETMLIFEEQ CREQERYGEE FERNNQSEEA DKELERYIKL
     KCRLGEIYDS KIHLEEDLRT QVEDYRETDR KMNSLRPDLI QLRNIRDQYL NWLNHKGVRQ
     KRINDWLGTQ SDSLDDTYVL KGDEKNLPHQ DETYWFVGEL SRTLAEEMLQ GKAPGTFLIR
     ESSKQGSYAC SVVVNEEVKH CMIYRTPHGY GFAEPYDVHC SLKDLVLHYR LHSLVQHNDA
     LDVRLSHPVH AKSAATETTY PCLCVSLYAA YV
//