ID   A0A3Q3VNL4_MOLML        Unreviewed;       167 AA.
AC   A0A3Q3VNL4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=Modulator of smoothened {ECO:0008006|Google:ProtNLM};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000003431.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000003431.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3VNL4; -.
DR   STRING; 94237.ENSMMOP00000003431; -.
DR   Ensembl; ENSMMOT00000003484.1; ENSMMOP00000003431.1; ENSMMOG00000002752.1.
DR   OMA; FASHWHR; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR037663; Mosmo.
DR   PANTHER; PTHR31186; MODULATOR OF SMOOTHENED PROTEIN; 1.
DR   PANTHER; PTHR31186:SF1; MODULATOR OF SMOOTHENED PROTEIN; 1.
DR   Pfam; PF18800; Atthog; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           27..167
FT                   /note="Modulator of smoothened"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018537914"
FT   TRANSMEM        65..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        101..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   167 AA;  18306 MW;  CFDA514CEC1F1C36 CRC64;
     MDKLTVISGC LFLAADIFAI ASIANPDWIS TGDSAGSLTV GLVQQCQTIH GRDRNCIPPQ
     LPPEWITTLF FIILGIISLT VTCGLLVMSR WRREATRYAR WIAFMGMVLF CMAALIFPMG
     FYIDEVGGQP YKLPNNTVVG SSYVLFVLSI FFTIVGLLFA GKVCLPG
//