ID   A0A3Q3VVF8_MOLML        Unreviewed;      1040 AA.
AC   A0A3Q3VVF8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000005578.1};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000005578.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000005578.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3VVF8; -.
DR   STRING; 94237.ENSMMOP00000005578; -.
DR   Ensembl; ENSMMOT00000005677.1; ENSMMOP00000005578.1; ENSMMOG00000004392.1.
DR   OMA; PCGYMLM; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005158; F:insulin receptor binding; IEA:InterPro.
DR   GO; GO:0008286; P:insulin receptor signaling pathway; IEA:InterPro.
DR   CDD; cd01257; PH_IRS; 1.
DR   CDD; cd01204; PTB_IRS; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 2.
DR   InterPro; IPR039011; IRS.
DR   InterPro; IPR002404; IRS_PTB.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR10614; INSULIN RECEPTOR SUBSTRATE; 1.
DR   PANTHER; PTHR10614:SF7; INSULIN RECEPTOR SUBSTRATE 2; 1.
DR   Pfam; PF02174; IRS; 1.
DR   Pfam; PF00169; PH; 1.
DR   PRINTS; PR00628; INSULINRSI.
DR   SMART; SM01244; IRS; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00310; PTBI; 1.
DR   SUPFAM; SSF50729; PH domain-like; 2.
DR   PROSITE; PS51064; IRS_PTB; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          18..119
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          151..255
FT                   /note="IRS-type PTB"
FT                   /evidence="ECO:0000259|PROSITE:PS51064"
FT   REGION          256..399
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          433..459
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          941..975
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..302
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        320..390
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..457
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        952..975
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1040 AA;  112874 MW;  5AA238D3475A68CC CRC64;
     MASPPATGGH LLFNEANGVK RCGYLRKQKH GHRRFFVLRE PTERCPARLE YYESEKKWRN
     KSAPRRAITL DSCLCVNKRA DAKHKHLIAL YTKDEYFAVA ADNEQEQESW YDVLTELIAE
     GKVYDSPAST SSLVGFEEAN YGLIAPAISA YKEVWQINLK SKGLGQIKNL TGVYRLCLSS
     RNISFVKLNS ETAAVTLQLM NIRRCGHSDS FFFIEVGRSA VTGPGEFWMQ AEDSVVAQNI
     HETILEAMKA MKELSEFRPR SKSQSASTNP ISVPTRRNLN NLPPSQTGLL RRSRTDSMAA
     TSPVRKFMSC RIRTASEGDG SVTRPVSMSI SMNGSPTSPN SGNHLSRSHT LSSGRTCRML
     ESSSNLHHSR SMPVSNSPPA ASSPISMSPR GGAATCTPDK ARRPFSCSAS ISGSLSDTGF
     MLCDDYSSSP GDPRFLPLTR SDTPDSLSST PPSRDTSDPC SYMIMEGGNG SRSGACGEGL
     KFEKAYRKRT HSLTTPRQQT VVAPLSSASL DEYTLMRMAQ GQNSHSASPK VCYPEDYGDI
     EIGSSRSSSS NLADDGYMPM TPGVASQSGK MDNYVPMSPM CVSAPKQIVN PRVHPQAAAN
     GGYKTNSPCS SSLEDSGYMR MWCGSKSSME SPDKHGEYMN MSPGNPPPLQ TPPDYYLGLL
     AGETASVRPV YQAGSLTLPA KLQASKPEES NQYVLMSPQS LRQRVGDADY YSVMQPSAAQ
     SSPLGRPNRL SLDTLRTLPS MNEHPLPGEP RSPGEYINID FSCARFSPPS AISTESQSSS
     LGYNGGGPGR SSLADYINLE LNSHSPKEAN TPVKQLDTLP ELSRCPCSEE DGVYHLDDDK
     QSQGLRDEVK NNYTEMTFGM TSCLPALENC DSAGSREKRL SLEDQEVPEG IGVFVIGATS
     PTVDPDCSAK VIRANPQGRR RHSSETFSST ATVTPVFPSF ARGDTMKRHS SVENISSRSS
     EGSDEEYGSP VNRQGSAGYP NGLNYIALNL LDNRNVEKCE DLAGFKPTSS CKGGINGLRG
     TPYVCLGFKE AATTAKGERG
//