ID   A0A3Q3VY68_MOLML        Unreviewed;       406 AA.
AC   A0A3Q3VY68;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=GPR180/TMEM145 transmembrane domain-containing protein {ECO:0000259|Pfam:PF10192};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000008201.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000008201.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q3VY68; -.
DR   STRING; 94237.ENSMMOP00000008201; -.
DR   Ensembl; ENSMMOT00000008352.1; ENSMMOP00000008201.1; ENSMMOG00000006366.1.
DR   OMA; DHSCTEK; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR   InterPro; IPR047831; GPR180/TMEM145.
DR   InterPro; IPR019336; GPR180/TMEM145_TM.
DR   PANTHER; PTHR23252:SF29; INTEGRAL MEMBRANE PROTEIN GPR180; 1.
DR   PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR   Pfam; PF10192; GpcrRhopsn4; 1.
PE   4: Predicted;
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        170..191
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        289..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        356..377
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          109..372
FT                   /note="GPR180/TMEM145 transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF10192"
SQ   SEQUENCE   406 AA;  45405 MW;  847C721F50D71981 CRC64;
     MVGSEYVFDV ADIKCVCVGD SGLLVCRLDN SPLATEKDSR LLLYHDTDSD LDNLSCSERL
     AKAQLTISLS QEEHNQTIPR QSSPTAWKAL YADRYTCQES AVIPSHPDLA FTVLLLNADS
     AGNPLEHFSA EEAGLQSFYF LLLLAYFIAC CIYIQPLYQA LRKGGPMHTV LKVLTTALAL
     QGCSAMCNYV HLARYSRDGV GIPLMGSLAE FWDMVTQVSM LYMLLSLCMG WTLSRGRKPQ
     SRPLQWEQSP ASTAVSVGGV VTQGVLLLWE QYSESESEHH SYHAQQSLAG LLLMALKVLL
     ALLLASVLYQ IISTERSTLK RDFYLCFAKG CFLWFLCHPI LFLTSVIFNE HQREKVVTIG
     VILCQSISMV ILYQLFLSRS LYWEVSSLSS VSLPLTMSRT NQRGRY
//