ID A0A3Q3VYI8_MOLML Unreviewed; 588 AA.
AC A0A3Q3VYI8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000004152.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000004152.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3VYI8; -.
DR STRING; 94237.ENSMMOP00000004152; -.
DR Ensembl; ENSMMOT00000004228.1; ENSMMOP00000004152.1; ENSMMOG00000003320.1.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF21; PROTEIN 4.1 HOMOLOG; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR PRINTS; PR00935; BAND41.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 166..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..255
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 352..382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 395..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 483..588
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 413..438
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..588
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 588 AA; 65571 MW; F767B83F8EB5B8E3 CRC64;
DNVCEHINLL EKDYFALSFR DLVIQVKCVG DPVPSLLSTG VPWNFSFNVK FYPPDPAQLS
EDITRYFLCL QLRQDIVSGR LPCSFATHTV LGSYTVQSEL GDYDPDDVSE LCFAPNQTKE
MEEKIMELHK TYRGMTPAEA EMHFLENVKK LSMYGVDLHH AKVKTIIQPV CVCVCVCVCV
CVCVGLLVYR DRLRINRFSW PKILKISYKR NNFYIKIRPG EVRPIHSDTT EEESTLCKRL
WKVCVEHHSF FRSVSIRRKL LSLGSKFRYS GRTQIQSRRV SAQISRPAPN FPRCISKRNM
CLLACLPACL PACLPACLPA CLSNVLLIIL LFQTSEKVER VFLMIEPCDQ DQPMGDEPQV
ATGNLVGAPP CNPPPPPPGA CMAHDVTRDW TCDGDSSIAV SQSKHPVDKS EVSVNDDDDD
FDDDEHSNQD SDDDASDASE DVISVLAQAA VEDIMEVVLR QAQSSGSSDA NRDNINMNYA
ISPSEQKLTS MEGSPRTPSA LASQPAVSLP QHHPGNKDSP DSEDSEEDET RWMLGENSPP
PSQPHPTSRC SPCLAGQMQT SDHSDDDTNE PEFLQEVTHQ TETCSNNP
//
