ID A0A3Q3VZF3_MOLML Unreviewed; 783 AA.
AC A0A3Q3VZF3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=F-BAR domain only protein 1 {ECO:0008006|Google:ProtNLM};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000008886.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000008886.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane, clathrin-coated pit
CC {ECO:0000256|ARBA:ARBA00004283}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004283}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004283}.
CC -!- SIMILARITY: Belongs to the FCHO family.
CC {ECO:0000256|ARBA:ARBA00011064}.
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DR AlphaFoldDB; A0A3Q3VZF3; -.
DR Ensembl; ENSMMOT00000009044.1; ENSMMOP00000008886.1; ENSMMOG00000006852.1.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005905; C:clathrin-coated pit; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR028565; MHD.
DR InterPro; IPR018808; Muniscin_C.
DR PANTHER; PTHR23065:SF6; F-BAR DOMAIN ONLY PROTEIN 1; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF10291; muHD; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS51072; MHD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT DOMAIN 1..239
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 528..783
FT /note="MHD"
FT /evidence="ECO:0000259|PROSITE:PS51072"
FT REGION 273..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 345..389
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 429..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 494..523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..446
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..518
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 86383 MW; 58E8880ED253FA9A CRC64;
GDKNAGFDVL YHNMKHGQLA TKELAEFVRE AAVEETYSKS MSKLAKMASN GSPQTFAPMW
DVFRVSSDKL ALCHLELMKK MNDLIREINK YGEEQVKIHR KTKEEMVGTV EAVQALQIQN
GHLQKSKEGY HAKCLELDRL RKEGAPQKEL EKAELKSKKA AESFVLCIEK YNRVGGEFEQ
KMSESSQKFQ EIEEAHLRQM KQLIKGYFHS IEDTHVQVGQ LQVHEEFKQN VENIGIDNLI
QKFAEQKGTG KERPALMSFE EYMTTLAPEG GKKNRAKAFR IPGLGKRDKE PDSEKENNFY
SSDSDFDDDE PKKFHIQIRP VASSSRSNLA ATEKELKATV GALTLPPNRG VSVKRHLSNS
STAERCSEEG DGASHRLSST ASGSDSLFGP PLESAFKSKS FDGREQLREQ SVFGASEILI
DNLAAFSSES SSPENIEDSG LDSPSHQPLG PSPEPVGWAA WPPVSQSKEQ TQTLGRALFA
HSAAQEGADA LELCPQPVTS PAPLSPPPPP PPAPSRGPSP ISLSTQEAWP VAAAITEYIN
AYFKGGQHNC LVKITGDLMM SFPAGITRIF AASSNVPVLS FRLVNISRID RFLPNQKLLY
DPSQSDPDTR DFWFNMQALQ LYLQREAEVN PQASYYNVSL LKYQDPGRAP LLLSAECQRS
GTVTRVSLDY HCCPATAPST QLTAVQVLLP LDHTATDLQC QPPASRNAEE RRLLWKLVPG
SGTLCASWQC LEVPRGPPPS LAVQFVGSGT SLSGMDVELV GSCYRMSLVK KRFATKYMAG
CSL
//
