ID A0A3Q3W0M8_MOLML Unreviewed; 942 AA.
AC A0A3Q3W0M8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000009481.1};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000009481.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000009481.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR AlphaFoldDB; A0A3Q3W0M8; -.
DR STRING; 94237.ENSMMOP00000009481; -.
DR Ensembl; ENSMMOT00000009649.1; ENSMMOP00000009481.1; ENSMMOG00000007344.1.
DR OMA; LYYSQAK; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 6.10.140.1910; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR PANTHER; PTHR47735:SF8; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 5; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01459; KCNQCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 108..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..161
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 307..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 108..337
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 433..613
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..666
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..798
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 825..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 914..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..420
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..700
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 842..874
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 942 AA; 104497 MW; BD1DC3271261FD82 CRC64;
MLRRHTGDGN GGPGLWQKTS PGRRVQEYLL NDVESGRGTM SNSVQAGDGF LCAAAAGAMG
VERKQGARLS LLGKPLTYNA QSGRRNARYR RLQNYLYNVL ERPREWAFVY HAFVFILVFG
CLVLSVFSTI PAHQEFSSHC LLILEFVMIV VFGLEYIIRI WSAGCCCRYR GWQGRLRFAR
KPFCVIDIIV LIASVAVVSA GSQGNIFATS ALRSLRFLQI LRMVRMDRRG GTWKLLGSVV
YAHSKELVTA WYIGFLVLIF SSFLVYLVEK EFNKDFATYA DALWWGTITL TTIGYGDKTP
QTWTGRLLSA GFALLGISFF ALPAGILGSG FALKVQEQHR QKHFEKRRNP AASLIQCVWR
SYAADENSVS IATWKPHLKV LHTCSPANQK LTFKERVRMA SPRGQSMKSR QMSINDRQRC
SPGNEVVGGT ELMGGSPAKV QKSWSFNDRT RFRPSLRLKT QTRTTAQDVD TGMTTEDSFD
ERGCHCDITV EDLSAPLKAV IRAVRIMKFH LAKKKFKETL RPYDVKDVIE QYSAGHLDML
CRIKSLQTRV DQILGKGQIP VDKKIRDKLH PDGETLEGMS MLGRVCKVER QVTSIESKLD
SLLDVYRQVL QKGPSAVTLS SLPLFELDNQ RHSSDYRTTI INRDLPSPRG GDPVGVGRRN
SGSISHSLNV NARGLRLILA PVDDDDPPDS APPSYPPSTA SLSPSPLLRP DSPYPTLVTP
KISSKKPYFP DLPPPPSSSA SFNLQLPTIL HPSHHQCSDD PISDDQGTLD PSVVLGTHVD
AGQEGDNQGS RAQEKAQLRD NAGLKSDGVW RRHFSLNVNP LLLLSSKPDA SPPDWDGSGR
NALSTHDLSQ PLTNRAPDLS SAINNSSSSN SSERVNAHAG LRNWDEAELL ISDCKLQTVE
EHFNFLPEES SSRSGFLQTV EEATPHPKGN SDFLSQSHIQ LA
//
