ID   A0A3Q3W175_MOLML        Unreviewed;       351 AA.
AC   A0A3Q3W175;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=FMN hydroxy acid dehydrogenase domain-containing protein {ECO:0000259|PROSITE:PS51349};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000007688.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000007688.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2-hydroxyoctanoate + O2 = 2-oxooctanoate + H2O2;
CC         Xref=Rhea:RHEA:67940, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:133514, ChEBI:CHEBI:176689;
CC         Evidence={ECO:0000256|ARBA:ARBA00029327};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:67941;
CC         Evidence={ECO:0000256|ARBA:ARBA00029327};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2;
CC         Xref=Rhea:RHEA:16789, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240,
CC         ChEBI:CHEBI:35179, ChEBI:CHEBI:58123; EC=1.1.3.15;
CC         Evidence={ECO:0000256|ARBA:ARBA00029325};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16790;
CC         Evidence={ECO:0000256|ARBA:ARBA00029325};
CC   -!- COFACTOR:
CC       Name=FMN; Xref=ChEBI:CHEBI:58210;
CC         Evidence={ECO:0000256|ARBA:ARBA00001917};
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DR   AlphaFoldDB; A0A3Q3W175; -.
DR   Ensembl; ENSMMOT00000007834.1; ENSMMOP00000007688.1; ENSMMOG00000005473.1.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005777; C:peroxisome; IEA:UniProt.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR000262; FMN-dep_DH.
DR   InterPro; IPR037396; FMN_HAD.
DR   InterPro; IPR008259; FMN_hydac_DH_AS.
DR   PANTHER; PTHR10578:SF137; 2-HYDROXYACID OXIDASE 1; 1.
DR   PANTHER; PTHR10578; S -2-HYDROXY-ACID OXIDASE-RELATED; 1.
DR   Pfam; PF01070; FMN_dh; 1.
DR   SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
DR   PROSITE; PS00557; FMN_HYDROXY_ACID_DH_1; 1.
DR   PROSITE; PS51349; FMN_HYDROXY_ACID_DH_2; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          11..272
FT                   /note="FMN hydroxy acid dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51349"
SQ   SEQUENCE   351 AA;  39346 MW;  9D247ED96AEBC317 CRC64;
     MNWRLIQGVP RLRPKIVCVS DFEEEARKVL PKSVYDYYHS GPEEQRTLAD NIAAFNRCFL
     KYGFLIPFCV GMCTVRMPIL CCCNITALRL CFYPACQAVG IGMMLSSWAT STIEEVMSAM
     TAKSGTGGVL WLQLYIYKNR ELILSLVQRA EEAGYKVIFV TVDMLYLGRR WDNMRDQFKL
     PPHLSMSNFS TASLAFSEEN YGNNSGLAVY VAKAIDPTLC WDDITWLKNH THLPLIVKGI
     LNGEDAVQAV NYDVDGVVVS NHGARQLDGV PAMVCVCICV LLWSCLMPPG HIRKGDPVTW
     ILANRDPQIT MASGSIDYTC FWTTTLHISL DLQILHTLGL SNTQIFLHGV Q
//