ID A0A3Q3W3M5_MOLML Unreviewed; 1027 AA.
AC A0A3Q3W3M5;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000010831.1};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000010831.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000010831.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3W3M5; -.
DR STRING; 94237.ENSMMOP00000010831; -.
DR Ensembl; ENSMMOT00000011015.1; ENSMMOP00000010831.1; ENSMMOG00000008352.1.
DR OMA; FMEVSKW; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04389; RhoGAP_KIAA1688; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR45876; FI04035P; 1.
DR PANTHER; PTHR45876:SF1; RHO GTPASE-ACTIVATING PROTEIN 39; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 30..58
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 643..823
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 834..1022
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 73..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 414..447
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..271
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..307
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1027 AA; 115107 MW; D62625D7A1E0526E CRC64;
ERMYANLLTG ECVWDPPQGV CIKRTGDNQW WELFDPNTSR FYYYNVSTQR TVWHRPQGCD
IIPLAKLQTL KQASADNSPG RNSGVSREGS TSSSLDQELS EKQTCKQLYH SATRLLIHFF
SCLFCLSSFP LITSSVLSSP LRTSPFRWNT GTKERMLIKV TDREPSFLAH QGNGYSPCDP
PAPAAPSGGG TTSRTRRSSG GKPPPEPDSP HVLYSDRRQS PFLKRAELGV TGTQRRSSVD
SQPPSPHYPY EPPLYEEPPS EYQPPPIYEE PPTDMHLTDS SSVYGTGKSP ANKSSVPLYH
SPKQGQSPYG QLVLTRQKCL EKTQNLEYSP VGKEYVKQLV YVEQSSSSPR FKAADRLMRY
GTTGIYGGSS GGSFTLQHSQ SLIRDPHLLL DYSGDDGMGG QRLLYEDTVS WTSSHSHSLS
SSSTGGPGAF SPGGHRKRKN RKPSLPQELA RCGGLEGELS GTASEAMLAQ ARLAWEAQQL
MKQRSSWDSG QERGGTQSGG SKDGYESDGA VPLPLPGPVV RAFSEDEALA QGDAHHWKRS
TFDRLGFPQA LLEKSLSVQT NLATPEPYLH PSQSEDLGAC AQFEASRNAR NMMPSASCGI
FPEFTLRKPS SETDIENWAS KHFNKHTQGL FRRKVSIANM LAWSSEPIKK PMIVTTDRTV
KREAVDIFKL IQTYMGDRRS KADPVSVALE VVVRGWSNQG LRDELYIQLC RQTTENFRYD
SLERGWELMA ICLAFFPPTP RFHSYLEGYI YRHMDPLNDT KVYAKLTPLE ILKLCKYPFF
FFATGVAISS YAKYCYRKLT KAALTGAKKG LQKPCLEEIK HARNAIFSPS MFGSSLEEVM
ALQKERYPDS QLPWVQTRLS EEVLGLNGDQ TEGIFRVPGD IDEVNALKLQ VDQWKIPTGL
EDPHIPASLL KLWYRELEEP LIPHEFYDEC ISHYDNPEAA VNVVLGLPHI NKLVLCYLIR
FLQVFAQPAN VTITKMDVNN LAMVMAPNCL RCQSDDPRVI FENTRKEMSF IRVLIQRLDT
SFMDGIL
//
