ID A0A3Q3W540_MOLML Unreviewed; 2225 AA.
AC A0A3Q3W540;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000006787.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000006787.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR STRING; 94237.ENSMMOP00000006787; -.
DR Ensembl; ENSMMOT00000006912.1; ENSMMOP00000006787.1; ENSMMOG00000005289.1.
DR OMA; RDELTQN; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR PANTHER; PTHR19229:SF190; RETINAL-SPECIFIC PHOSPHOLIPID-TRANSPORTING ATPASE ABCA4; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..42
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 653..673
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 693..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 729..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 758..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 834..855
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1335..1356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1643..1665
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1695..1713
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1725..1748
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1754..1779
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1791..1809
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1837..1859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 925..1155
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1901..2133
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 2225 AA; 252076 MW; CFFEB1FECC7F971E CRC64;
MGAGRQVKLL LWKNWTTRRR QRVRFLMEIM WPVMLFMGLM WLRRVNPLYR QHECHFPNKA
MPSSGVLPWI QGIFCNANNP CFQYPTRGES PGLVSNYNNS ILARLYTDAQ ELLFSDTEFQ
QIGRLWRELN AMSNFMDTLR THPDQVLGRG IKVETILKDD ETLTSYLLRD IPLTESVVTH
LVNAHIRPEQ FAFGVPALHL KDIACSLNLL ERFLIFPSRR GLYAVRNAMC ILTPQRLQII
EDKFYANVDF FKLFRLLPLV LDIHSEGIDI RLWVQVISAT SDKLRELHQR NSTRELLQVM
TPLFQNNLSF RQVMAAASSL VCGYSEGAFS RVTSFNWYED NNYKAFLGIS SSRGSGHYTY
DNNTTSFCND LMKELESNPA TRIVWNSVKP MLMGHILYAP DSPAVRTIIR NANTTFEELE
RLRTMGKAWE EVAPQIWDFF QNGVQVKMIR DTIRNPSVMD FIDRSLEEAP FSSKHILNFL
HNGPPQDRPT DMPDFDWRDI FNLTDRLIRM LNQYGECVIL DKFVALPDED TVTHHALDLL
RDTKFWAGLV FENMYPWTTS VPPHVKFKIR MDIDAVERTN KVKDRYWDPG PRADPMDDLR
YVWGGFAYLQ DMIEHGIIKT QTGKEWPLGV YLQQMPYPCY VDDLFMLTLN RCFPIFMVLA
WVYSVSMIVK TIVLEKELRL RETLKAMGVT NGVIWSTWFI DSFLMMGTST ALLTAIIMGG
RVLNYSNAVI LFLFLLTFTT ATIMQCFLLS VFFNQANLAA ACCGIVYFTL YLPHIFCFAW
QEHITKDMKI LVSLLSQVAF GFGTEYLSRY EEQGQGLQWD NIQTSPLEGD EFSFLTSICM
MGLDTILYAV LAWYLDHVFP GQYGIGRPFY FPFLPCYWLN SVAPALGTSN IPKTQSTPCP
YRALMSLLYA GHSFFETEPE LLKGVCIKDL VKVFGSGTRP AVDGLSISFY ESQITAFLGH
NGAGKTTTMS ILTGMFPPTS GTAIIYGKDI CTDMDSIRQS LGMCPQHNIL FHMTVAEHIL
FYSLLKGRPI AEAEEEVENM LQDLGLPHKR DELIQNLSGG MQRKLSVALA FVGGAKVVIL
DEPTSGVDPY SRRSIWDLLL KYRAGRTVIM STHHMDEADL LSDRVAIISQ GRLYCCGSPI
FLKNCFGAGF YLTLVRRMKH DAPKASCDCT EDCSCKCSKC SKFKVKSFPH LTGDLESITA
LIQHHVPQAR LIEAIGQELT YLLPSRNFQA RAYASLFREL EETLVDIGLS SFGVSDTSLE
EIFLKVTADG NETNRKFIQG ADGTLHTNGQ GLCDVPEGNA GRGSYQVKGL CLTIKQFFAL
LIKRLHHTTR SYKDFFAQIV LPASFVFLAL TFTLIVPPFG EYPSLTLTPW MYGRQYTFFS
NERPMDAQMR YFGEVLLNKP GFGTRCMVDE PLEDFPCNNI TTEWEMPLVN PVLIDKLARP
EWTSLRPSPD CQCSTPKKLT MLPVCPEGAG GLPPPQRIQS TGDVLMDLTG RNISDYLVKT
YAGLIKTSLK SKYWVNEQRY GGISVGGQLP VLELQPKIIQ DVAAQLGRLL NVTGGKYSKQ
TLKDVRTFLR YMETQNNVKV WYNNKGWHAM VSFMNVANNA ILRANLPKGA NLDEYGITAI
NHPLNLTKEQ LSEITVLTTS VDAVVAICVI FAMSFVPASF VLYLIQERVT QAKHLQFVSG
VSPLVYWMAN FLWDMVNYTI SAAMVVEIFI FFNKKCFTSP TNLQPLIALL MLYGWSVTPM
MYPMSFIFSV PSTAYVSLSC INLFIGINSS AITFILDLFE GTTALYKLNQ LLKTVLLIFP
HYCLGRGLID MAMNQALTDI YARFGEDYSP DPYSWDFIGK NLFCMAVEGF VYFILTILFQ
YRFFLDHWTS DRPKPPFLDE DVDVAEERER IYKSEKTNDI LQIRDLSKTY TGTIIPAVDR
ICIGVSPGEC FGLLGVNGAG KTTTFKMLTG DIDVTSGEGS VAGHCILTNI LDVHQNMGYC
PQFDAIDELL TAREHLHLYA RLRGVPEAEI SRVAEWAIQK LGLSQDAGRS AATYSGGNRR
KLSTAIAMIG CPVLVLLDEP TTGMDPLSRR FLWNSIMSVI RDKRAVVLTS HSMEECEALC
TRLAIMVNGS FKCLGTIQHL KYKFVVLFNL LLTFPGCIQR EKHYNTLQYK ISSSSLARIF
QMVLANKDKL NIEDYSVSQT TLDQVFVNFA KQQSREDDTI VLHPKAAGAQ RYVDTNPIKI
LGKLG
//
