ID   A0A3Q3W5T6_MOLML        Unreviewed;       594 AA.
AC   A0A3Q3W5T6;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Rho-GAP domain-containing protein {ECO:0000259|PROSITE:PS50238};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000009583.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000009583.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3W5T6; -.
DR   STRING; 94237.ENSMMOP00000009583; -.
DR   Ensembl; ENSMMOT00000009752.1; ENSMMOP00000009583.1; ENSMMOG00000007418.1.
DR   OMA; GDSGMKW; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR000198; RhoGAP_dom.
DR   PANTHER; PTHR14963; RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED; 1.
DR   PANTHER; PTHR14963:SF4; RHO GTPASE-ACTIVATING PROTEIN 40; 1.
DR   Pfam; PF00620; RhoGAP; 1.
DR   SMART; SM00324; RhoGAP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50238; RHOGAP; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          242..441
FT                   /note="Rho-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50238"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..39
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   594 AA;  67567 MW;  9C6AAEDCC1335D02 CRC64;
     MSVEPWASTQ DQAAAEDTHS THEPSSQDQE QEQHPDKLCL DSFWSEVETI KQGSKGEQEE
     QWLADAGLSN LISEDSEHVD NAVLLSTLTR TQAEAVQRRL DSYTLSLRKR NKPAPRDVRD
     VFNSPINQVR TVTPEHQRGA PKEEFFITDV AYCEQAVIFL KQAKLGQNNS QRRKEESTLP
     RVICPKCRLG VTRIQDLSHT DMKKVRQLAL IDMTALCDLL ELEVKRQKTS KRKIPESTLF
     GVPLATLLEN DQKIKPNTST PLFLQTLLSF LEKKGVDSEG ILRVPGSQSR IKLLQQNLET
     NFYAGLVSWD EVSPNDAAAL LKKFIRELPA PLLTTEYLNT FSAVRDITEL KQKLHMLNLL
     ILLLPEPNRN TLKALLEFLS KVVSREKRNR MNLWAVATIM APNLFLHKAV PSRLTEGAEK
     GQAEKAADVM RLLIRYQDLL WTIPNFLMSQ VRRLNENSSR RYQFYDRRLK NLLRKIHADS
     RDKTDKNSSQ LCRTVKIQVG DAVSGTMEYQ LNINSRASDL LAQFHHQSLR SPDNGKGKVR
     RCDAAQCVDD HIFLCVFCAG EHCLDPDTHL LDLYNSNNGG EWVIKLKPNA SRGL
//