ID   A0A3Q3W682_MOLML        Unreviewed;       694 AA.
AC   A0A3Q3W682;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0000259|PROSITE:PS50021};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000009753.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000009753.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the hook family.
CC       {ECO:0000256|ARBA:ARBA00006946}.
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DR   AlphaFoldDB; A0A3Q3W682; -.
DR   STRING; 94237.ENSMMOP00000009753; -.
DR   Ensembl; ENSMMOT00000009924.1; ENSMMOP00000009753.1; ENSMMOG00000007535.1.
DR   OMA; RGQLDTY; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0031122; P:cytoplasmic microtubule organization; IEA:InterPro.
DR   GO; GO:0030705; P:cytoskeleton-dependent intracellular transport; IEA:InterPro.
DR   Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR   InterPro; IPR001715; CH_dom.
DR   InterPro; IPR036872; CH_dom_sf.
DR   InterPro; IPR008636; Hook_C.
DR   InterPro; IPR043936; HOOK_N.
DR   PANTHER; PTHR18947; HOOK PROTEINS; 1.
DR   PANTHER; PTHR18947:SF37; PROTEIN HOOK HOMOLOG 2; 1.
DR   Pfam; PF05622; HOOK; 1.
DR   Pfam; PF19047; HOOK_N; 1.
DR   SUPFAM; SSF116907; Hook domain; 1.
DR   PROSITE; PS50021; CH; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          6..121
FT                   /note="Calponin-homology (CH)"
FT                   /evidence="ECO:0000259|PROSITE:PS50021"
FT   REGION          659..694
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          180..426
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          461..644
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        659..684
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   694 AA;  81391 MW;  18FB80EF167D6E6F CRC64;
     MSLDKAELCD SLLTWLQTFQ VPSCSSKRDL TSGVAIAYVL HRIDPFWFNE TWLGRIKEET
     GANLRLKVSN LKKILKSMLE YYHDVLSHQV SDEHLPDINL IGELEDVTEL GKLVQLVLGC
     AVSCEKKQEQ IQQIMTLEES VQHVVMTAIQ ELLSKEPSSQ PGSPETYGDF DFQSRKYYFL
     SEEADEKEDL SHRCRDLEHQ LSAALEERLS LQAETRSLKE KLSRCDTLDA STTAITSKKL
     LLLHTQMEQL QEENYRLENS RDDLRVRGER LEREVTELQH RNEELTSLAQ EAQAFKDEMD
     ILRHSSDRVN QLESLVETYK RKLEDLGDLR RQVRLLEERN TVYMQRTCEL EEELRRANAV
     RSQLDTYKRQ AHELHTKHTA EAMKAEEWQF EYKNLHDKYD ALLKEKERLI SERDTLRETN
     DELRCAQVQQ RCLSLCQLPT FYDSATLVRL QSENKMLCVQ EETYRQKLVE VQAELEDTQR
     SNNALESQDR LNQQQISELH RQVEELQKAL QEQDSKTEDS SLLKKKLEEH LEKLHEAHSD
     LQKKREVIDD LEPKVDSNMA KKIDELQEVL RKKDEDMKQM QERYKCFMEK ARTVIKTLDP
     KQPVSATPDI QALKNQLTEK ERKIQHLESD YEKSKSRRDK EEKLIISAWN SMGMSLHQRV
     SGERLGPSNQ TMSFLAQQRQ STNARRGLAR HHPR
//