ID A0A3Q3W8D1_MOLML Unreviewed; 476 AA.
AC A0A3Q3W8D1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=ADP-ribosylation factor GTPase-activating protein 2 {ECO:0000256|ARBA:ARBA00039244};
DE AltName: Full=Zinc finger protein 289 {ECO:0000256|ARBA:ARBA00043100};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000010623.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000010623.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}. Golgi
CC apparatus membrane {ECO:0000256|ARBA:ARBA00004255}; Peripheral membrane
CC protein {ECO:0000256|ARBA:ARBA00004255}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004255}.
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DR AlphaFoldDB; A0A3Q3W8D1; -.
DR Ensembl; ENSMMOT00000010806.1; ENSMMOP00000010623.1; ENSMMOG00000008194.1.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR CDD; cd09029; ArfGap_ArfGap2; 1.
DR Gene3D; 1.10.220.150; Arf GTPase activating protein; 1.
DR InterPro; IPR037278; ARFGAP/RecO.
DR InterPro; IPR001164; ArfGAP_dom.
DR InterPro; IPR038508; ArfGAP_dom_sf.
DR PANTHER; PTHR45686; ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED; 1.
DR PANTHER; PTHR45686:SF10; ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 2; 1.
DR Pfam; PF01412; ArfGap; 1.
DR PRINTS; PR00405; REVINTRACTNG.
DR SMART; SM00105; ArfGap; 1.
DR SUPFAM; SSF57863; ArfGap/RecO-like zinc finger; 1.
DR PROSITE; PS50115; ARFGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}; Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW Zinc {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-ProRule:PRU00288};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00288}.
FT DOMAIN 11..117
FT /note="Arf-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50115"
FT COILED 218..252
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 476 AA; 52519 MW; E454EC98664C4B74 CRC64;
MATEPNKTEI LTIFKRLRSV PTNKACFDCA AKNPSWASIP YGVFLCIDCS GIHRSLGVHL
SFIRSTELDS NWNWFQLRCM QVGGNANAMA FFRQHGCSTN DTNAKYNSRA ARMYREKIRQ
LANAALSKYG TDVSINQVRQ FWGIHYCMLF CVADVKPSII GKKKPMAAKK GLGAKKGLGA
QKVSSKSFSE VEKQAQVAEK LREEQATEAK KQVEESIVAS MRLAYKELEI DRKMEEKKLK
NLEGKKREQA ERLGMGLGTR STVSHSVMSE MQVIEQESPV GAKSSSRSKL DMFDEPGFTS
GPPKYKDNPF TVGDGFGSRW DTEGGTASFT SSWALEKEEP KEEVTISSIQ PIGERYLPTS
AQRHVRSTEL LCSSEARQKF ANAKAISSDM FFGRESSAEY DAKTRLESMS GSTSISSADL
FGDGTDHKGR ASGFDSVLPS GPDIAQFKQG VKTVAGKMAV LANGVMNTIQ DRYGSY
//
