ID   A0A3Q3WFS4_MOLML        Unreviewed;      1911 AA.
AC   A0A3Q3WFS4;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000016076.1};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000016076.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000016076.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00983}.
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DR   Ensembl; ENSMMOT00000016342.1; ENSMMOP00000016076.1; ENSMMOG00000012249.1.
DR   OMA; YDHYIPL; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd08697; C2_Dock-D; 1.
DR   CDD; cd13267; PH_DOCK-D; 1.
DR   Gene3D; 1.20.58.740; -; 2.
DR   Gene3D; 1.25.40.410; -; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR037809; C2_Dock-D.
DR   InterPro; IPR027007; C2_DOCK-type_domain.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR021816; DOCK_C/D_N.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   PANTHER; PTHR23317; DEDICATOR OF CYTOKINESIS DOCK; 1.
DR   PANTHER; PTHR23317:SF81; DEDICATOR OF CYTOKINESIS PROTEIN 11; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   Pfam; PF14429; DOCK-C2; 1.
DR   Pfam; PF11878; DOCK_C-D_N; 1.
DR   Pfam; PF00169; PH; 1.
DR   SMART; SM00233; PH; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS51650; C2_DOCK; 1.
DR   PROSITE; PS51651; DOCKER; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
PE   3: Inferred from homology;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          164..271
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          622..801
FT                   /note="C2 DOCK-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51650"
FT   DOMAIN          1472..1911
FT                   /note="DOCKER"
FT                   /evidence="ECO:0000259|PROSITE:PS51651"
FT   REGION          273..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          428..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1911 AA;  218791 MW;  07CD4B0891C3F8B8 CRC64;
     MSEVRKFTKR LSKPGTAAEV RQSVSEAVRS TVDLEQPKII EPLDYEAVVF QRKAQIHIDP
     HRDLLLCPVD DVSESQISRQ RRTVVLSVPQ NAEREARSLF AKECIKMYNT DWHVINYKYE
     AYSGDFRLLP SKGLKTDKLQ AYVFEIDEDA KDEDSASLCS QRGGIMKQGW LQKANINSSL
     SVSMKVFKRR YFYLSQLPDG SYILNSYKDE KNCKETKGSI YLDSCIDVVQ SPKMRRNGFE
     LKMQDRYSHF LAADTETEME EWVATLKQAL QSSTEASQER RNGGETLDYD DTASQGKGEG
     LLESLGRNLY PELTKYARET DQLNRINRND SRQKLFSLDP ETQRLDFSGI EPDVKPFEER
     FGRRIVVSCH DLTFSLQGCI SEKGDGVLTN VEPFFISLAL FDVSKSCKIS ADFHVDLNPP
     CVREMLTDTS VLHSPSSDSE GGGRGEGGVR MMGIFSVTNP HADIFLVARV EKVLQNGITH
     CSEPYIKTSD INKTAQKVLK TAKQTCQRLG QYRMPFAWAA KQVFKDAQGS LDMDGKFSPL
     YRQDSSKIST DDIIKLLADI RKPEKSKLQT IPGQLNVTIE CAPPDLSSIN VAFEDGCERV
     SVEIKEFLPE EAKYNYPFTT YKNQLYVYPL QLKYENQKTF TKARNIAVCI QFRDSDDEGA
     APLKCIYGKP GDSLFTSSTN AAVLHHSQSP EFYDEVKIEL PVHIHEKHHI LFTFYHISCE
     TSSKASSKKR EGVESLVGYS WMPLLKDGRM QSVELQLPVA ATLPAGYLLW PMLSIYMLTL
     NDSHCWVENA KTLFKMRIHV ASTIYAQDLY LHKFFQHCQL MRTTSEGNPA ELIKYLKCLH
     ATETHVIINF LPTVLMQLFE VLTAATKEAH EIAVNCLRVI IHIVSRCHEE GLENYLRSFV
     KYVFVTNNPA SGNLVTTHEV LAIAVTATLK HTADFNTSNK LLKYSWFFFE IMAKSMAQYL
     QEGNRMKMPR AQRFPDSFHQ TLQSLVLSIM PHITIRHMEI PEEARSINLS LAITXXXXXN
     RGFAFSLVNH YMCHFGLKDP KVLSEMKFDF LMTVCNHEHF IPLNLPMAFG RTKLQRVQEQ
     SLEFSLTEEY CRNHFLVGLL LREVAEALQQ GPEVRQLAVS ILKNLLIKHA MDDRYTAFKP
     LKSLRTFSLY ADTLNAYWNK VSPQDIMNFL ISCSLLSLVF KNKHMLSSFW MFCLHRSQET
     CVSKLFSSDK KAQTMPAMRC NRASLMQTKI QQFSTMETSL TLNIGTGLSE VEIHHQALLE
     GSMSTEVCLS VLDVLSLFTQ CFKTQLLDSE GHNPLMKKVF DVYLNFLKVS QSEAALRHVF
     AALRSFINKF PSVLFKGRVM LCEALCCEVL KCCVSKLASL RAEASGLLYL LMRNNYEYTK
     RKTFLRMHLQ IIIAVSQLIS DVALTGSSRF QESLSIINNF ANSDKAMKST AFPSEVKGLT
     MRIRTVLMAM AQMREHEKDP EMLLDLQYSL AQSYASTPEL RRTWLDSMAR AHLKNGDLSE
     AAMCYIHVSA LVAEYLHRKK LFPSGLAAFK KITLNIEEEA AMREDTGMQD VYYTEEVLVE
     HLEVCVEALW KAERYELITH IAKLLIPIYE KRHKYEKLSR LYDTLHRAYN KIIEVIQSGR
     RMLGTYFRVA FYGQGFFEEE DGKEYIYKEP KLTGLSEISQ RLLSLYGEKF GQENVKIIQD
     SNKVNSKDLD SKFAYVQVTF VKPYFDEKEA PEKKTDFEKC HNINRFVFET PYTLSGKKHG
     GVEEQCKRRI VLTTASTFPY VKKRVEVVGE KQVELKPVDV AIDEMKARTA ELTKLCSSQG
     VDMIQLQLKL QGCVSVQVQV SKVKDLKDVF RRFVQACSMA LDINERLIKE DQFEYHEGLK
     ANFKEMVKEL SDIIHEQIRG IHSEWRAKNF EVFLQFTKNL KALLKPLHQS R
//