ID   A0A3Q3WFS8_MOLML        Unreviewed;       348 AA.
AC   A0A3Q3WFS8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Adenosine deaminase domain-containing protein {ECO:0000259|Pfam:PF00962};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000016081.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000016081.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H(+) + H2O + N(6)-methyl-AMP = IMP + methylamine;
CC         Xref=Rhea:RHEA:16001, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:58053, ChEBI:CHEBI:59338, ChEBI:CHEBI:144842;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:16002;
CC         Evidence={ECO:0000256|ARBA:ARBA00036622};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q3WFS8; -.
DR   STRING; 94237.ENSMMOP00000016081; -.
DR   Ensembl; ENSMMOT00000016347.1; ENSMMOP00000016081.1; ENSMMOG00000012271.1.
DR   OMA; RPQFKPY; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0019239; F:deaminase activity; IEA:InterPro.
DR   CDD; cd00443; ADA_AMPD; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF42; ADENOSINE DEAMINASE-LIKE PROTEIN; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          13..338
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   348 AA;  39089 MW;  FC5D9024CE7C7699 CRC64;
     MEIEAEDFYR QLPKVELHAH LNGSVSFQTI EKLSRRKPHL NIERSMTAIG KGQRRSLDEC
     FEVFKVIHQL VDAEEEILMV ATDVIKEFAA DGVKYLELRS TPREEKNTGL TKRLYVETIL
     KAIQQCKKEE VDIDVRFLVA IDRRNGAEVA METVKLAEEY MLSSDGLVVG LDLSGDPTVG
     HGKDLLPALQ KAKNCGLKLS LHLSEVPSQL EETDLLLSLP PDRIGHGTFL HPEVGGSQNL
     VDKVVQNNIP LELCLTSNVK GQTVPCYSNH HFKYWYQLGH PCVICTDDKG VFSTDLSQEY
     QLAASTFSLS REAVWTLSQQ AIDCIFAPDA VKQQLRQKWA DVQSQVSE
//