ID A0A3Q3WG22_MOLML Unreviewed; 555 AA.
AC A0A3Q3WG22;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=E3 ubiquitin-protein ligase RNF10 {ECO:0000256|ARBA:ARBA00035131};
DE AltName: Full=RING finger protein 10 {ECO:0000256|ARBA:ARBA00035390};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000013653.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000013653.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RNF10 family.
CC {ECO:0000256|ARBA:ARBA00008117}.
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DR AlphaFoldDB; A0A3Q3WG22; -.
DR Ensembl; ENSMMOT00000013876.1; ENSMMOP00000013653.1; ENSMMOG00000010467.1.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd16536; RING-HC_RNF10; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039739; MAG2/RNF10.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR12983; RING FINGER 10 FAMILY MEMBER; 1.
DR PANTHER; PTHR12983:SF9; RING FINGER PROTEIN 10; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 196..237
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..545
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..75
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..526
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 555 AA; 62469 MW; 4BF0F75027EFB0A5 CRC64;
MPESSAALCP DLGLGTRHCT KINMEKNPSS SSTSTKVPPR SSSTGPAPGE TKAKTESKNN
GGSKRYSRKR EPSFPKTDTF QGPRRTNSQK GKNFDKRPSQ RGGRQYGVTG GGRREEVCMK
LVHRVTPDGG YSCWGRRNKW GHKHKPFNKE LFLQANCQFV VTDDQDYKAH FTDPDTLVNW
DCVQQVRIYS HEVPSCPICL YPPVAARITR CGHIFCWPCM LHYLSLSDKS WSKCPICYEA
VHTADLKSVI AMETRQYAVG DVITMRLMRR EKGSLVAMPS SQWVKVEEPV RFGDARLSPY
SKLLLTSPAQ ALSLVEEEKA VLRAQLSQEE DAQGCFIQSA LCLLQVTKPK VLYVRDDVKH
MFHHIFLLLL CLPAADGCQQ MFLHPVNVRC LLREYGSLEA SPDSITATVV EIVGHTVTEE
IRRRHRYLAH LPLTCEFSIC ELALQPPVLS KVTLDTFADE LEKRKRMRQK KVREEKRREK
RIEMEENKKQ GKYPEVHIGL ENLQHFPAFG SPPYSSSPPV QPDVVFNPPA PLSSSPASGK
SPSLTPAVGI FLSEF
//
