ID   A0A3Q3WK41_MOLML        Unreviewed;       659 AA.
AC   A0A3Q3WK41;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=G protein signaling modulator 2 {ECO:0008006|Google:ProtNLM};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000015268.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000015268.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the GPSM family.
CC       {ECO:0000256|ARBA:ARBA00006600}.
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DR   AlphaFoldDB; A0A3Q3WK41; -.
DR   STRING; 94237.ENSMMOP00000015268; -.
DR   Ensembl; ENSMMOT00000015519.1; ENSMMOP00000015268.1; ENSMMOG00000011648.1.
DR   OMA; PEDRSFH; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0030695; F:GTPase regulator activity; IEA:InterPro.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   InterPro; IPR003109; GoLoco_motif.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR45954:SF3; G-PROTEIN-SIGNALING MODULATOR 2; 1.
DR   PANTHER; PTHR45954; LD33695P; 1.
DR   Pfam; PF02188; GoLoco; 3.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 2.
DR   Pfam; PF13176; TPR_7; 2.
DR   SMART; SM00390; GoLoco; 3.
DR   SMART; SM00028; TPR; 6.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50877; GOLOCO; 3.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          65..98
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          244..277
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          459..486
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          503..559
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        462..482
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        532..550
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   659 AA;  73659 MW;  05116A770F4E988B CRC64;
     MDTSGAVVST RAKEESFHVR YRMEVSCLEL ALEGERLCKV GDYRAGVSFF EAAIQVGTED
     LQMLSAIYSQ LGNAYFHLHD YTKALEFHRH DLTLTRTIGD LLGEAKASGN LGNTLKVLGR
     FDEAVVCCQR HLDIARDIND KVGQARALYN FGNVYHARGK SICWSGAEPG DFPEEVMTAL
     RKAAEYYEAN LTIVKELGDR AAQGRTYGNL GNTHYLLGNF RKAVASHEQR LLIAKEFGDR
     AAERRAYCNL GNAYIFLGEF EVAAEHYKRT LQLARQLKDR AVEAQACYSL GNTYTLLQDY
     ERAIDYHLKH LIIAQDLNDR IGEGRACWSL GNAHTALGNH DQAMHFAEKH LEICKETGDR
     SGELTARMNV SDLQMVLGLS YSTNNSTLSE NKDIDYNLHG ARPRMSRRHS MENLELMKLT
     PDKMNWNSDI LTKQSKPSMA KSSSKLFFVN RLRGKKYKTG GSSKVLQDTS NTLESSQTPR
     LSPDMLGDEG FFDLLSRFQS NRMDDQRCSV QDKGSRLSLN SGPESPPKAI RKSVSESANV
     SCSQGPRLKE TSAAGGSLPG LRLNQNNSQA VLSHLMANAD SAEPDDQFFD MLVKCQGSRL
     DDQRCAPPPP PVRGPTVPDE DFFSLIMRSQ AKRMDEQRVT LPSLQHKDTH FQIQNKVTS
//