ID   A0A3Q3WN29_MOLML        Unreviewed;      1189 AA.
AC   A0A3Q3WN29;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000019226.1};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000019226.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000019226.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3WN29; -.
DR   STRING; 94237.ENSMMOP00000019226; -.
DR   Ensembl; ENSMMOT00000019546.1; ENSMMOP00000019226.1; ENSMMOG00000014547.1.
DR   OMA; CGSDITR; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR   GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR   CDD; cd18027; DEXHc_SKIV2L; 1.
DR   CDD; cd18795; SF2_C_Ski2; 1.
DR   Gene3D; 1.10.3380.30; -; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR048392; MTR4-like_stalk.
DR   InterPro; IPR025696; MTR4_beta-barrel.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016438; SKI2-like.
DR   InterPro; IPR012961; Ski2/MTR4_C.
DR   InterPro; IPR040801; Ski2_N.
DR   PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR   PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08148; DSHCT; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF21408; MTR4-like_stalk; 1.
DR   Pfam; PF13234; MTR4_beta-barrel; 1.
DR   Pfam; PF17911; Ski2_N; 1.
DR   PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 2.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM01142; DSHCT; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT   DOMAIN          282..438
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          553..718
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          138..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          218..240
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..240
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1189 AA;  132808 MW;  E8C8C59785D6901D CRC64;
     MVSHLLPVDV PPAGPMDLPL SLLEMGCSGR FELITQPIPG QPLPPQSTLP HGLPPTSLSL
     ETEVEKRFLR DPSWLPLHDT DFAFQKVAQR EVNVDSLLNC SPSPLHSGLS VLRDPTTGML
     MDFTEVLLEN TGLSAKNSLS FQRQPGPPSE SLRGSNTNYP FLPGGMEELS LDQIKKKSEL
     EEDIDFEKDL LRIPPGFKAG MDFTGKAAVK SVLLYPQDAV SPSSPPEKGK EDKCKPKENP
     EESKKWAILV NISSPCNDFY KRIPNPAFKW PFELDLFQKQ AILRLEAHDS VFVAAHTSAG
     KTVVAEYAIA LSQKHMTRTI YTSPIKALSN QKFRDFKNTF GDVGLLTGDV QISPESSCLI
     MTTEILRSML YNGSEVIRDL EWVIFDEVHY INDAERGVVW EEVLIMLPDH VSIILLSATV
     PNAVEFSEWI GRIKKRHIYV ISTAKRPVPL EHYLYTGNST KTQKEMFLLV DAVGNFLTKG
     YYAAVDAKKE RTSKHAQSFG AKTTSQNTTA SQDRAVWLTL LHFLSQRQQT PVVAFTFSRT
     RCDENARSLD SMDLTTSIEK AEIHSFFQKS LIRLRGGDRQ LPQILLMRNL LKRGIAVHHS
     GILPILKEVT EMLFSRGLVK VLFATETFAM GVNMPARTVV FDSIRKHDGT GFRNLLPGEY
     IQMAGRAGRR GLDATGTVII LCKAGVHEMA DLHVMMLGKP TILQSQFRLT YTMILNLLRV
     EALRVTDMMR RSFSESHRDT QTHEQKIRQL KQTVSSLPPL DMEGQLSDML PYYHTVTELR
     TTTKALQRAI LESVNRLKAL SVGRVVVVNN KQHFNALGVI LQVSNDSVNR TFTALIICEK
     GNEEGEGNGS HADALPHLCN TALFIPEGPC SHTVQKLKFE EVSAITVKTL KVIPDRIIDN
     YNKRQQPRFR LDPPGQAIST ATQELLRLAE ASPGGLASLD PVNDLQLKSV DVVEGSMRLR
     VLQDSLKEFN CIHSPTFAEQ VRERMSVQEE LDRLLFLVSD QSLSLLPEYH QRIKVLQSLQ
     YIDSSGAVQL KGRVACQISS HELLLTELLF ENVLSPLAPE ESAALLSCLV FTQNTQGIER
     VLSVAQRIGE LQKDCGIPQT AEEFVGQLKF GLTEVVYCWA RGMPFAEIAQ LTDVQEGTVV
     RCIQRLDEVL KDVRQAARIV GDSVLGSKME KASLAIRRDI VFTASLYTH
//