ID   A0A3Q3WNT1_MOLML        Unreviewed;       819 AA.
AC   A0A3Q3WNT1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Taste receptor type 1 member 3 {ECO:0000256|ARBA:ARBA00040705};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000014077.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000014077.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 3 family. TAS1R
CC       subfamily. {ECO:0000256|ARBA:ARBA00038492}.
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DR   AlphaFoldDB; A0A3Q3WNT1; -.
DR   STRING; 94237.ENSMMOP00000014077; -.
DR   Ensembl; ENSMMOT00000014305.1; ENSMMOP00000014077.1; ENSMMOG00000010775.1.
DR   OMA; WALGMKF; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd06363; PBP1_taste_receptor; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   PANTHER; PTHR24061:SF435; TASTE RECEPTOR TYPE 1 MEMBER 3; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..819
FT                   /note="Taste receptor type 1 member 3"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018786008"
FT   TRANSMEM        569..591
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        603..625
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        645..664
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        685..718
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        730..751
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        758..777
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          596..791
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   819 AA;  90728 MW;  ABCB3981003DB646 CRC64;
     MFGPSTLLVL LWAFKLSCST PEWFQNISTS LFSLPGDIML GGLFPINELT SNLSQRSEPD
     NISCESIDQY GLGLAIVMKY AVDEINAHQT LLPGITLGYE IHDTCRQSAV IVKPTISFLT
     AKSSKVLSVE CNYTNYEPAI SAVIGPRNSE LVSVIGKLLG FFLMPQISFG ATSDKFSDKL
     LYPSFFRTVP SDKWQVEVMV LLLLNFDWNW VAVVGSEEEY GQQGVQEFSK IAANKSVCVA
     YQGLIPVYTD PEPVVKTIID NIIATNVEVV VVFSLPGQAQ VFFKEVIRRK LRGVWIGSTS
     WAIHNQITSL PNIETIGTII GFSDKIHTLD LLTAYTEELL SKLSAQNAHT SPPASTRSNL
     LNPCPECWNL SPANISMVTE PVLQRTAFSV YAAVYSVAQA LHNLLGCNST TCMQRSEIKI
     YPWKLLGALK NMSVDINGTH LVFDSDGNPN IGYNVVEWVW KDSGLVDFME VGSFNKKLDI
     NSSLFKWHTP NSQVPQSTCS AVCGKGQVRR VKGFHSCCFD CIDCLPGTYQ ATDEAIQCTA
     CPQGQWSQER STNCTEPTFD VLSWDTYEAL VITLAAVLVV VCQGAVGVVF LKHRDTVCRL
     QLPLTSILQT VALSIITSIS LQILFVSEFP QIAAPRLHIL RGPASWLFLL ICCALQAGIC
     GWFVQEGPSL SEHLANMKIN FVRSFLACPV LPLPGFAIMQ SFITAMALVS FMCTFMAVKP
     LHQYNLARDI TFSSLIYCVF WVTFIPVYLG LNDKYRSIVH ISFTLASDFG LVAAYYFPKC
     YFLLRKPELN TADHFCTFLE GVPPTPAQEE PQTETESQQ
//