ID A0A3Q3X0Y4_MOLML Unreviewed; 852 AA.
AC A0A3Q3X0Y4;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RHD domain-containing protein {ECO:0000259|PROSITE:PS50254};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000024493.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000024493.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3Q3X0Y4; -.
DR Ensembl; ENSMMOT00000024903.1; ENSMMOP00000024493.1; ENSMMOG00000018563.1.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR GO; GO:0043227; C:membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.60.40.340; Rel homology domain (RHD), DNA-binding domain; 2.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR008366; NFAT.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR032397; RHD_dimer.
DR InterPro; IPR011539; RHD_DNA_bind_dom.
DR InterPro; IPR037059; RHD_DNA_bind_dom_sf.
DR PANTHER; PTHR12533; NFAT; 1.
DR PANTHER; PTHR12533:SF6; NUCLEAR FACTOR OF ACTIVATED T-CELLS, CYTOPLASMIC 3; 1.
DR Pfam; PF16179; RHD_dimer; 1.
DR Pfam; PF00554; RHD_DNA_bind; 1.
DR SMART; SM00429; IPT; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS50254; REL_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT DOMAIN 384..512
FT /note="RHD"
FT /evidence="ECO:0000259|PROSITE:PS50254"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 319..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 745..780
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..852
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 745..767
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 852 AA; 92430 MW; BD4114166A842471 CRC64;
LPPPPRGHAL RGWGASCYPD VRTPPTSAPA LNEQPVIQEL QSHPARFATA DQYQHVDYQT
QRPEYRALEN PRAFDCPSIQ ITSIAPTNHV EPGCSLEALP LGGAVGGAVG GAVGGYPELS
RSRGQLYLPL DPCYRDTALS PSPCSSLSSR SWMSDLSSCE SFSHVYDDVE GELRDAARLA
MGSPLGSPMG SPGCGGGAFG VELWQQKYQH PLPYSPALSP HQSPRQSPCH SPRTSVTEES
WLHRRPTSRP SSRPTSPCGK RRHSSADPYA RSPSPHHSPS PTPGASPRGS VTDDTWVGSP
AGILGSLFMS GFQELDVPSK TRRTSGSQLG LLASKGDPGL EPFQDSPAEE AREQDGLAEL
FLQVPSHFSW NKPRPGNPPL FRASSPPPLD WPLPNQFEQC ELKLEVQPRS YHRAHYETEG
SRGSIKAAPA GHPVVKLTGY SEQPVSLQLF IGTADDRYLR PHAFYQVHRV TGKMVTTSCQ
EKIMGCTKVL DIPLLPENDM AASIDCNTRV KVVFRVAVPQ PDGRMLWLQT SSVPVECSQR
SGQELPQVES FTPASCSVDG GQELLITGSN ISAQSRVVFT EKGPDGRSMW EIDARVVPEK
SSGSNIVVEV PPYCKKTKDL IQVQFYISNG KRRRSQAQSF TYLPAVRRHL PAGVKQERWK
ADNISHKPPG LSCQVPSRNH VISPDGVYYD SCDVPVHCGP PSQSMPRLPH PPPSLMYPHT
SSSSSAPHQT FVPLQTAVMP IQISTMPPQA SSGGPQREPS PSLSSRRAFE TPADPLKDSL
LSTSGEVLSI KQEPEDLQPN LGSLGLQEIT LDDVNEIIDR DIGSLSSGTR PHQFDWGDKP
SDAAAAFSGG PR
//
