ID   A0A3Q3X552_MOLML        Unreviewed;       816 AA.
AC   A0A3Q3X552;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=G-protein coupled receptors family 3 profile domain-containing protein {ECO:0000259|PROSITE:PS50259};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000017124.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000017124.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
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DR   AlphaFoldDB; A0A3Q3X552; -.
DR   STRING; 94237.ENSMMOP00000017124; -.
DR   Ensembl; ENSMMOT00000017407.1; ENSMMOP00000017124.1; ENSMMOG00000013045.1.
DR   OMA; KCTRFNF; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   CDD; cd15283; 7tmC_V2R_pheromone; 1.
DR   Gene3D; 3.40.50.2300; -; 2.
DR   Gene3D; 2.10.50.30; GPCR, family 3, nine cysteines domain; 1.
DR   InterPro; IPR001828; ANF_lig-bd_rcpt.
DR   InterPro; IPR000337; GPCR_3.
DR   InterPro; IPR011500; GPCR_3_9-Cys_dom.
DR   InterPro; IPR038550; GPCR_3_9-Cys_sf.
DR   InterPro; IPR017978; GPCR_3_C.
DR   InterPro; IPR000068; GPCR_3_Ca_sens_rcpt-rel.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   PANTHER; PTHR24061:SF528; C-FAMILY ODORANT RECEPTOR OLFCD2-RELATED; 1.
DR   PANTHER; PTHR24061; CALCIUM-SENSING RECEPTOR-RELATED; 1.
DR   Pfam; PF00003; 7tm_3; 1.
DR   Pfam; PF01094; ANF_receptor; 1.
DR   Pfam; PF07562; NCD3G; 1.
DR   PRINTS; PR00592; CASENSINGR.
DR   PRINTS; PR00248; GPCRMGR.
DR   SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR   PROSITE; PS50259; G_PROTEIN_RECEP_F3_4; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   G-protein coupled receptor {ECO:0000256|ARBA:ARBA00023040};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        547..571
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        583..605
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        617..641
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        661..680
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        706..729
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        741..761
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        773..796
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          547..811
FT                   /note="G-protein coupled receptors family 3 profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50259"
SQ   SEQUENCE   816 AA;  89651 MW;  75E5D3E4266045D3 CRC64;
     MTLVSLIQLY IFTEKLLLTL DKFFSALSAC SLSLPVLEKK GDVVVGGLFS LHDMVMEPSL
     FFTSTPTPTQ CTSMKDSGSG GAMSSKGTCH GAIPAVIGDG GSTQSLVVAR FLGVFHVPQV
     SYFSSCACLS DKKEFPTFLR TMPSDFFQVD ALIQLVKHFG WTWVGVIAGD DDYGRGGANI
     FADGVRKLGA CVALHETIPK TQAQTAISTM ISKIRTSGAR VILVFAVEQD TVRLFDEVLR
     HEGLAGIQWL ASEAWSTAAV LSNPKKYHHI LQGSMGFAIR RAYIPGLQDF LLRLHPSSPD
     AREDPFLVPF WEEVFQCSQG VPDSQERNVG KPSCSGAEEL GGVKNIYSDV SQLRISYNVY
     KAVYVIVHAL KAMRSCVKGK GPLPQHACPD IENIQPWQLL HYITQVEYVN PLGDEIKFDE
     NGDPAAMYDL ISWQLTSSGE MEFVTIGKFD ETTSAGKKEL LIQEQNIVWN GNQTQVPLSV
     CSSKCPPGTR KAIRPNLPIC CHDCVVCTAG EINAIECERC LPEFWSNAER TVCIPKQVEF
     LSFSDTMGIT LMVISLIGSF CTCIVVIIFF CHRTTPIVRA NNSDLSFLLL FSLTLCFLCS
     LTFIGRPSDW ACMLRHTAFG ITFVLCISCI LGKTIVVLMA FKATLPGSTA MKWFGPGWQK
     AIITSSTLVQ VLICIVWLAV APPTPRQLMP RESAIIILLC DEGSPIAFVL SLGYIGLLAC
     LCYLLAFLAR KLPDNFNEAR LIAFSMLIFC AVWVAFVPAY ISSPGKYSTV TEVFAILASS
     YGLLGCIFAP KCYIILIRPE KNTRKHLMSK SAKDKF
//