ID A0A3Q3X5R0_MOLML Unreviewed; 2482 AA.
AC A0A3Q3X5R0;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000020649.1};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000020649.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000020649.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR STRING; 94237.ENSMMOP00000020649; -.
DR Ensembl; ENSMMOT00000020993.1; ENSMMOP00000020649.1; ENSMMOG00000015712.1.
DR OMA; DNCEVRD; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005537; F:mannose binding; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0007041; P:lysosomal transport; IEA:InterPro.
DR CDD; cd00062; FN2; 1.
DR Gene3D; 2.10.10.10; Fibronectin, type II, collagen-binding; 1.
DR Gene3D; 2.70.130.10; Mannose-6-phosphate receptor binding domain; 15.
DR InterPro; IPR000479; CIMR_rpt.
DR InterPro; IPR000562; FN_type2_dom.
DR InterPro; IPR036943; FN_type2_sf.
DR InterPro; IPR013806; Kringle-like.
DR InterPro; IPR009011; Man6P_isomerase_rcpt-bd_dom_sf.
DR InterPro; IPR044865; MRH_dom.
DR PANTHER; PTHR15071:SF0; CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR; 1.
DR PANTHER; PTHR15071; MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER; 1.
DR Pfam; PF00878; CIMR; 14.
DR Pfam; PF00040; fn2; 1.
DR PRINTS; PR00013; FNTYPEII.
DR SMART; SM01404; CIMR; 14.
DR SMART; SM00059; FN2; 1.
DR SUPFAM; SSF57440; Kringle-like; 1.
DR SUPFAM; SSF50911; Mannose 6-phosphate receptor domain; 15.
DR PROSITE; PS00023; FN2_1; 1.
DR PROSITE; PS51092; FN2_2; 1.
DR PROSITE; PS51914; MRH; 14.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00479};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..2482
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5018635700"
FT TRANSMEM 2285..2306
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 159..302
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 308..457
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 462..613
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 619..754
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 757..906
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 914..1053
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1056..1195
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1201..1336
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1340..1482
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1488..1630
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1632..1781
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1793..1973
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 1882..1930
FT /note="Fibronectin type-II"
FT /evidence="ECO:0000259|PROSITE:PS51092"
FT DOMAIN 1976..2110
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT DOMAIN 2136..2262
FT /note="MRH"
FT /evidence="ECO:0000259|PROSITE:PS51914"
FT REGION 2354..2377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2413..2482
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2357..2377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2465..2482
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1887..1913
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
FT DISULFID 1901..1928
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00479"
SQ SEQUENCE 2482 AA; 272379 MW; BED7DB4C1B6186D0 CRC64;
MLSQCKADRW PPLKLVLRLV LFLGCVLAWS GAVEDSSLWY QDLCGYKWEA IDKDHKVTYT
LKLCESSPST SCGLAAAVCA RNLTTNTDGS VGEYAPPLHT GMVLHHGSCW RDASSSCCCV
VCVLQGTPEF VAISQCVHYL EWKTYAACKN DKFKPQKEVP CYVFDTDGKK HDLSPLIKVS
DGFLVDDGDD SIDFYINICR TLNLPGKSCP EGSAACLVTS HGSYNMGSPT KQLELLSSDR
LRLQYEAIAD ASTSEICKGH NPAVTITFIC PSSRHAGSTP KMMAESNCRY EVDWVTEYAC
HRDYLESNTC KLSNEQHDMS IDLTPLTLSS TDIPYNAHSD PTDGGESYIY YLNVCGEVST
NECGQDKFIS SCQVKTSQDV KKVAGKYENQ TLRYSDGDLT LIYPDGAKCS SGFQRMTIIN
FECNKNASNG GRGSPIFAGE TDCTYYFDWE TAFACVKEKE DLLCRVRDEN KHYDLSALTR
FPGSDVSGNW EAVNALSPKS DSRFYLNVCH KVLESRGTAG CPVDASICAI DKDHKAISLG
SFLTSPQKTN TGNDIRLVYT DGGFCNNKKM RIQTILTLKC KPGDLESAPI LRSISSDGCV
YELDWYTAAA CVLSKTQGNN CKVEDAQADL SFDLSPLTKA DGGFYNLTIG NYDYYINVCG
PVKAVNCPDK AGACQVEQSS WSLGEANSRL SYYNGLIKLT YSNGSQYNNE QHTLRSTLIS
FLCDPEAGAG QPEFQIEDKF TYNFRWYTSY ACPERPHECL VTDPDSLLQY DLSSLSRSTS
SSNWQVNDLS DSKNQRTYYI NICRPIIPVP GCDRQASVCQ ITFSKEFVSV SNMGVSKRGP
IIEGRDHLLL EFTDGSTCIS DSLRLTYTTR IHLVCSRGSQ SMSPQFLMYQ NCTATFRWET
RAACAITTTT NKNNTCAVVD PNTGFEFNLQ LLASKSGYRT SANGKDFLVN ICSDVAECGS
GNAGCELENG HSLSPVGLEK TLQYSTDGLL TLTYKGQLDG PTATRDTFTI NFACDPNSHP
GSLKLVREDI STLPERVVHD VLFEFSTALA CIPAPVDCRI IDPHGNEYDL RHLIRNGDDS
PWIAIDTDAV KSRSFYINIC RPLPPLNACP VGPLGACGMI DGKSYNLGYV QSRPQAAEDG
TISIVYQNGD RCGSTSHYST RIILQCDDNP GSPMFDREDG CEYVFIWRTS EACPITKSKG
ENCQVPDSRS GYVFNLSSLK GKDYQVRHDK YIYHLSVCGG LQREICSHGN DTVASCQVDG
VSQKIGGMSN QALSYVGDQL ILNYTNGETC HTIYQRSTEI YFSCHPDKHP GVPEFINETP
ECTYLFSWPT ALACIPVKTT SCSYNDGQGH SYDLSPLALD SRNWEVESST HDTQQRFYIN
VCRSLVQMEG SWNCPSSAAA CLKMGENYVS LGQVVSGPTW AMGVLQLRYI SGQACPDGSR
YRSSIIRLKC DKDKVDSRPT LISAIEDCVY TFLWLTAAAC PLNSTQHGDC RVTNPATGHL
FDLNSLSKEG GYTVYHHQEH RKMFRMNICG NVTNAGCSPD SAVCIKDAST AVSGGQVSRK
LSYKDHVVEL TYEGGNPCSA NPALTHKTVI HFICRPPKMG SAPPEPVLID SNSETCTHFF
SFHTPLVCEQ PVKCSVQNGS ALINLSPLIH ISGYYTATGT DIRYLPSINQ SPDFYINICQ
PLNPIPGVTC PPGAIVCMDP DNGPPVDIGR TTSGPEINPA TGEVSITYLS STKCAADPTQ
TYNSTIIFTC QRGLELGSPQ MLSLQGCVYL FEWATPIVCS DSTHIDGCKL TDSQLQFTFD
LSTLSGEVQV PVGSSVYHIN VCGEVAEPAC RKSAVCQVSS SGSKKFTSSF GISQAMTMDF
KHEEQAVLMK YGGGDPCPPG TSVGEVCVFP FTFMKESYTE CTKEGRTEGR KWCATTANYD
TDRKWGFCTS GKRQSSILFT CDQSAGHGEP QLFSETAGCS ATFQWRTSAV CPPRKMECKL
VSQHRTFDLR SLSSLTEPWK FSHHRDSYFI NLCQGIHGGS PGCPADATVC RRTASGKTQV
LGRVYTQKMN YTDDKIFVIY SGDGVCNGLK AKTVIQLSCG STVGQPTLLS VDEGTCEFVI
GWETRLACAV KQHEVDLVNG TIKVPDTGII LSLGALYFSH HQATGDIRPN GDRYIYHIQL
SGITNDSLSS CVGANICQVK LNGAYNRRIG SSSKAKYYIK GGSLDVMVPS ESKCGREKTK
MVSSTIMFYC NPSAGIGIPE FMLETAECQY LFLWHTDAVC TLTTVEAKTY YDDDSGTPLS
SRSQALGLLL TVLLVGLTVC LLGLLLHKRE RREMVIQKVA SCCRRGNQVS YKYSKISMDE
DGGEEEMEWL MEELEAPPTS SFSSSQGGRS NHGNGHIRTK AVNMDGLRSF SLDEQDDDSE
DEVLSVPGVR MVKSSGASRN STAHRSAFLQ EESDEDLVGL LEESDRKSKS GEARSSGFNH
GNNTAANRKR DEDDSDEDLL RV
//
