ID A0A3Q3X846_MOLML Unreviewed; 637 AA.
AC A0A3Q3X846;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Transcription initiation factor TFIID subunit 6 {ECO:0000256|ARBA:ARBA00040091};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000021679.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000021679.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TAF6 family.
CC {ECO:0000256|ARBA:ARBA00007688}.
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DR AlphaFoldDB; A0A3Q3X846; -.
DR STRING; 94237.ENSMMOP00000021679; -.
DR Ensembl; ENSMMOT00000022037.1; ENSMMOP00000021679.1; ENSMMOG00000016472.1.
DR OMA; MPEETCQ; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0000124; C:SAGA complex; IEA:InterPro.
DR GO; GO:0046695; C:SLIK (SAGA-like) complex; IEA:InterPro.
DR GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0016251; F:RNA polymerase II general transcription initiation factor activity; IEA:InterPro.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd08050; TAF6C; 1.
DR Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR Gene3D; 1.25.40.770; TAF6, C-terminal HEAT repeat domain; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR037796; TAF6.
DR InterPro; IPR011442; TAF6_C.
DR InterPro; IPR046344; TAF6_C_sf.
DR InterPro; IPR004823; TAF_TATA-bd_Histone-like_dom.
DR PANTHER; PTHR10221; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR PANTHER; PTHR10221:SF9; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6; 1.
DR Pfam; PF02969; TAF; 1.
DR Pfam; PF07571; TAF6_C; 1.
DR SMART; SM00803; TAF; 1.
DR SUPFAM; SSF47113; Histone-fold; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 12..78
FT /note="TATA box binding protein associated factor (TAF)
FT histone-like fold"
FT /evidence="ECO:0000259|SMART:SM00803"
FT REGION 142..194
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 506..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 596..617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 69313 MW; AE746262B5F7FC22 CRC64;
MAEERRQKPC SVILPTESMK AMAESIGVGQ LQEDSCIALS EEVSYRIKEI TQDALKFMHH
GKRRKLTTSD IDNALKLKNV EPLFGFQSQE FIPFRFASGG GRELHFYEEK EVDLSDIINT
PLPRVPLDVS LKHWLSIEGV QPAIPENPPP PKEQQKVEST EPLKVVKPGQ EDDGAIQGKG
QGATSADGKG KEKGLIRLKP RSTHELSVEQ QLYYKEITEA CVGSCEAKRA QEALQSIATD
PGLYQMLPRF STFISEGVRV NVVQNNLALL IYLMRMVKAL MDNPTLYLEK YLHELIPAVV
TCIVSKQLCL RPDVDNHWAL RDFAARLMAQ SCKTFSTTTN NIQSRITKTF TKSWLDDKTQ
WTTRYGCIAG LAELGPDVIK TLILPRLSVE GARIKAVMEG PVVSNIDKIG AEHVQSLLLK
HCASVIAKIR AQPDNVEQYR IDYGYLGPML CSHVMKARTQ AALQAQQVNR TTLTITQPRP
TLTVSQSGLS GSTGPRTPSI IKVPSSLTLM SPRPGTPSQP SPPATKYIVV GTSAGAASTQ
QVITISSSQS ASPVTSTVPS ATSTLQPLVK LEPGSGPGLT GSRPLQKYIV VSLPSSASSS
LETKSSVLPT SISSTPLEAG VKLERSESPA ASTQSPH
//
