ID   A0A3Q3XEP1_MOLML        Unreviewed;       840 AA.
AC   A0A3Q3XEP1;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=A kinase-anchoring proteins AKAP-5 and AKAP-12 calmodulin (CaM)-binding domain-containing protein {ECO:0000259|PROSITE:PS51893};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000021186.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000021186.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   STRING; 94237.ENSMMOP00000021186; -.
DR   Ensembl; ENSMMOT00000021542.1; ENSMMOP00000021186.1; ENSMMOG00000016116.1.
DR   OMA; NWEALIC; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005516; F:calmodulin binding; IEA:InterPro.
DR   GO; GO:0051018; F:protein kinase A binding; IEA:InterPro.
DR   GO; GO:0010739; P:positive regulation of protein kinase A signaling; IEA:InterPro.
DR   GO; GO:0090036; P:regulation of protein kinase C signaling; IEA:InterPro.
DR   InterPro; IPR028540; AKAP12.
DR   InterPro; IPR001573; AKAP_WSK.
DR   PANTHER; PTHR23209; A-KINASE ANCHOR PROTEIN 12; 1.
DR   PANTHER; PTHR23209:SF4; A-KINASE ANCHOR PROTEIN 12; 1.
DR   Pfam; PF03832; WSK; 1.
DR   PROSITE; PS51893; AKAP_CAM_BD; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        29..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          475..495
FT                   /note="A kinase-anchoring proteins AKAP-5 and AKAP-12
FT                   calmodulin (CaM)-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51893"
FT   DOMAIN          616..636
FT                   /note="A kinase-anchoring proteins AKAP-5 and AKAP-12
FT                   calmodulin (CaM)-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51893"
FT   REGION          152..664
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          752..779
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..221
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        252..318
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        341..355
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        356..377
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        412..431
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        440..459
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        460..477
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        490..505
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        506..525
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..540
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        555..582
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        617..662
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        760..774
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   840 AA;  92548 MW;  71282CAEB0CA0365 CRC64;
     YHKTSSRKQR SDRNKAEASN SQFCKSSRFI KFCFLLYFLG LMNDMIKHTP ISDKFLVLSV
     GQPDGVSVAQ KEEASETADT VQDEVAPQVN GDTAEKVSPD ASDISAVEEK AAEEKSDDAN
     EVGFKKIFRF VGFKFTLKKD KSEEKDPVKL LTVKDKEEEE EEVSKTEEQT KETEAATVES
     TGEEKEADKE ASPAEVNEDG DKTETTEAEE EAVKEAEPVK EVDTTQPAQE TTLSPFRKLF
     NGGLFSNLRK KSSIKKTKEE EDKEVPTEEG TAKTEETVPA VDETEASDKT EQETKEIEPE
     TPGEEKTEAK EEVPATPEEA KSESTTGPEV TPAPAAPTTD ENKPEDAKIE SSAEEENAPA
     ETTSEGELLS SQEKAKPQGS PLKKLFTGAG LKKLSTKKQK TKKDAETKFT ESGEQVTEQL
     QSSTDSAEAP KADSGPSSPE ESGEHVTASG ATRIESSQES HGEVTSDGEK KKEGIIAWSS
     FKKLVTPKKR VKRSSESEDE ATGEKQAKSA TLSSSESAPK MENNEKLVSS TEEPKKKMDT
     SVSWEALMCM GGPKKRTRKT SDSDDEETKI GEEMRQAAEG EQEGKTEAVV VCSQNSEPEG
     EVVSSPEPLS SPPERESAWD TLKRVVMPKN KAKVEEKPGE SLEQVQSDSE APKDESSFSF
     KKFLPGRRKK KVDKQASTDQ APWQHTLRLV TEQRLCHCLH LPFHLYSNPI LQHYHNMXXX
     XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXFS SPPPSPPPPP PHTHTHTHSL
     SHMHTVKHVR IPSGVLNVMY VQFVSDVPLP ALHQTKVCNL VECVSVHTCV PVFVCVCVVR
//