ID   A0A3Q3XH33_MOLML        Unreviewed;       520 AA.
AC   A0A3Q3XH33;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Caspase recruitment domain-containing protein {ECO:0000259|Pfam:PF16739};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000028275.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000028275.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   AlphaFoldDB; A0A3Q3XH33; -.
DR   Ensembl; ENSMMOT00000028755.1; ENSMMOP00000028275.1; ENSMMOG00000021369.1.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0002376; P:immune system process; IEA:UniProt.
DR   GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR   CDD; cd08811; CARD_IPS1; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   InterPro; IPR031964; CARD_dom.
DR   InterPro; IPR042144; CARD_IPS1.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   Pfam; PF16739; CARD_2; 1.
DR   SUPFAM; SSF47986; DEATH domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        498..516
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          6..94
FT                   /note="Caspase recruitment"
FT                   /evidence="ECO:0000259|Pfam:PF16739"
FT   REGION          107..142
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          168..296
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        266..296
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   520 AA;  55122 MW;  7A1BF1687DEE3BEA CRC64;
     MTFASDKLFN GYLRRNMPTI VSKVKVREII PHLPCLTGHD METIEAKRET CGNYDGMVLL
     LDCLKRRENW PEEFILALEQ CGHQTIADGI RNEYDNLRCI NNSNPSSPSA TVIRAHVHPP
     PSARPLSIPE SGGNKPAAQA SPSLEIPEHP VSQDAPLPEP VSEPAQIEVA PAPSTPPPSP
     ETIRTQPASA SPPPQGEIIY HQEPVENSES DIQDVSGDGD VSPDQVSAGN VVDTPQPVRP
     PRSPSPTETN SDMTDRSAVN MMTPEKPPVQ DTNPSADSNS AAVLQPEETS EPPAETAATT
     FPLLDTASMG PSLFDSTLCL SKPGELISTQ PQNHDSPTVC APILPGQPYS GNTARLEMSI
     AAATSAHVSA CSAATSTTVN TTSVLPCQEN GIALDPGEPE ENHYDSPLQS LGTQEVRVNV
     VQISEEPSIL NLDGQSSAPQ AQIFNGEAAK ENSPAAPLSN SAADTVLSVN APTADLSQEL
     KLLQDSEKTS SHTLATNTMY ILTAAGVGAC ALLMAWKFKN
//