ID A0A3Q3XN62_MOLML Unreviewed; 503 AA.
AC A0A3Q3XN62;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000025836.1};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000025836.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000025836.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the STAM family.
CC {ECO:0000256|ARBA:ARBA00009666}.
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DR AlphaFoldDB; A0A3Q3XN62; -.
DR Ensembl; ENSMMOT00000026275.1; ENSMMOP00000025836.1; ENSMMOG00000019593.1.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR CDD; cd21390; GAT_STAM2; 1.
DR CDD; cd11820; SH3_STAM; 1.
DR Gene3D; 1.20.5.1940; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45929; JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE; 1.
DR PANTHER; PTHR45929:SF1; SIGNAL TRANSDUCING ADAPTER MOLECULE 2; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF00790; VHS; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 16..143
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 204..263
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 266..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 474..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 335..369
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 487..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 503 AA; 55622 MW; 41CE712592FFDF56 CRC64;
MPLFTQNPFD QDVEKATNEN NTIDDWGLIM DICDKIGTTP NGPKDSLRSI MKRINHKVPH
VAMQALNLLG ACVSNCGKIF HLEICSREFA SEVRSVLGRA HPKVCEKLKA LMVEWADDFQ
KDPQLSLVTA TIKSLKEEGI SFPSSSSQYS SSWWPSGPLS QKNPFTQRAA HQTIEMSLQE
QKLQVETRPL TSDPPSYANG GGGQDVRKVR ALYDFEAAED NELTFKAGEL ILVLDDSDPN
WWKGENHRGV GLFPSNFVTT NLNAEPETVT SAERPGSPEE TIPETKVEPE PVFIDEGKMD
RTLALLQNAD PADPTPESPE LIQLEGACEQ MNPMIDEKLQ EIDRKHSELS ELNVKVLEAL
ELYNKLMNEA PFYTAYNKMQ SQYTPTMQGY LGAASAPYMP ATMAPAQPYT LPSDPPASLQ
SLPPTASAPP MSHLCFPHSV GMNTQYINQA AGAHYAPQVG VAMDMSTYHN SSVPHVSYPV
APPPHQAPQQ QQQQAAYYQQ PLL
//
