GenomeNet

Database: UniProt
Entry: A0A3Q4AC30_MOLML
LinkDB: A0A3Q4AC30_MOLML
Original site: A0A3Q4AC30_MOLML 
ID   A0A3Q4AC30_MOLML        Unreviewed;      2354 AA.
AC   A0A3Q4AC30;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   10-FEB-2021, entry version 11.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSMMOP00000001510};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000001510, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000001510}
RP   NUCLEOTIDE SEQUENCE.
RA   Yu H., Pan H.;
RT   "The genome of Mola mola.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSMMOP00000001510}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2019) to UniProtKB.
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DR   Ensembl; ENSMMOT00000001539; ENSMMOP00000001510; ENSMMOG00000001243.
DR   GeneTree; ENSGT00730000111187; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR   GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR   GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR   GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          1..302
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1430..1547
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          1663..1792
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2244..2288
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          50..71
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..161
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          374..397
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2173..2217
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2231..2253
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2319..2354
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          275..330
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          428..536
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          551..634
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          655..682
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          687..735
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          747..767
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          783..869
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          881..908
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          947..981
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          986..1006
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1035..1065
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1070..1132
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1159..1371
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1392..1412
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1441..1482
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1511..1531
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1569..1596
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1639..1708
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1712..1790
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1812..1923
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1931..1986
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2070..2146
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        129..157
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        380..397
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2173..2210
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2338..2354
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2354 AA;  271664 MW;  C2F0C7AC57741495 CRC64;
     MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVSSERT
     ETSAMKRENQ SLVESCDSLE KARQKVSHDL GVKEHMFEHN NILKLEWHSM LFLSSFHLLR
     YKNELDRSQP AGCSSLSSSE LQPYTTPQKS FTTPAPAHRH QDNRLEELQE KYSQEIEERK
     RLETELKVLQ VKLLTQSTAS VSHKDIAARQ GGSSIFPWQQ QDQAHSRQCQ DAMETPLKRR
     GTSLWEAHEE TPLKINQRMS CPRALQSPSG SSQQMEQLKT INQELRGRVS ELERNLSSHE
     KEIRSQTSKL QELQIQLNQA RKELTDRDKD LVKIRHETHA NDKHFSYCLT EEMSCQRHNA
     ESCRRALEQK LKEQERGSQK ELGQLQSSQQ ALEQQLNQTR TKLTQEIQQS KKDYNVLQAD
     MEKMCFQKNQ MVKEVEEQKQ KLLRSEQNLQ AYQNKEQDLH KKMEELQKEK NIVVVQLDQS
     SRRLSQLEEE KKSTDQSLKR TQGLLDDLKA KSEGQVEELK RLQSKLEQQT QASTQELLTI
     KKKFSDVETK NDRSQIELQK QTQEAEKLTK SLSVLEKESQ ELKSNLTASL KECDELKKEH
     QALLQWKNEK ESLVNEAEAV QKDLTDKIGN LEKSEKAKGD KASLSAHIDS LKGELLNKST
     ELEEREHQYK ELQSKFSEAG QKHTKDLENV AVQVKQLEAK VKELELRLQK ESARADQAER
     TNSELQDEHQ AACDLAHSKD QLLELGQAEI SQLRESLNQT IAQQEEQLNL VFMFQVSSMD
     QCLKVQEHLA AELQKQIKKL SDDEKEHKKI NEKKSEEIRQ LEEELKDLQS HTEEKQKLLR
     DTEAKVLFLE KEKNDLENTA KEAELYILQI VNLSFFFKTL QQTQTEKINN LLEQISSLDE
     ELTASRDAAK KLTALKSELD MVNQSHADLK KCMENLERSH SSTIEIKASL ENLLTEKNNL
     ISTLENEVKG LKEKMSNLSE THTLEMENVL NKEKHIKLQL DAAKQKVAAA KLESSSRREE
     IKTMKTTLTA ASRGLEERDD TIESLKEKLN KAEMEQAKMS DLLKEKTVAM NKIKVQLEML
     QMDLEDNETA MNSFDSQVEE LKGTIESLES QLAQNQTQMS DMEARLEESK AQVKPLSCMK
     FFILEISLRQ IIGDKDKSIN QMLQDKNNLE TTLKQLLDNK EQVETEIIQV NAQRKELEAC
     VAKLSEENKQ LQTTMKQLTE DKQKIDQITQ EKEEVELTLR QVNEQKAELD ITISQINQDK
     TRLEAILNEL TTEKQNSAAR LNQVVEEKLQ LEAHCNQLIE ENTKLQCSLN QLTEEKLLLQ
     KSIDRREGEV TSLKDENEVI QNALLSSEQE LQRLQEQLEM RDKRAEEEEN RERYKSSALH
     SDKLLWVHFK FLAQLSEERE TLNLQLQTSK CQLADVMEML EGLEMAKGGW DEKFLQRESE
     LKRVRSEKAN LEQHILGMES ELEILHEERT KLRDEVETQR KMGSGMEQQI QTLITETTQL
     RSELVSCTEE RDDLSQSLGQ WRDKVQNLEK TNCDTRNLIS ILEDDIRAGG KEFATDSFPF
     LHLKLLEQIK AMEQAISQQN GEREELIGQL DKITEDHTSA NQNTETMVGK IQALEGKVCC
     LSQSLEASLL EKGEIASRLN STQEEVQQMR TGIEKLQVRI ESDERKKRKM AELLKAAQRK
     FDSLQDRIDA LERERDDVEQ SLEEAVLQVF CCKHVEDEKR ELSDKLSELS ATLDNLRSEK
     EWMERELETK NREIEELKAV KEENRVKELE KGMREEAERQ TRIMDDLQQQ LQASWQKALS
     LEERSAETEG VRETMQTLLA EMEKERTCLQ TEGERLRCEA EEWEKERNNL RSSIEALKEE
     IQDCKAYIKA EEEEKKNLLS TLSSVEQQRE NLQGDLVSVE GEKEKLEQES KVLAVEKEKL
     QSSLSVIAKE HHDTQQTLSS LTQQNHRIEE EKQKLETEKE ALLSLLSAIE VEKNDLSSAL
     SALEQEKMCL NPIISLVELH GPIESTDKNM YPKRVNFQMN QYATDRSDDD FLFKFISTWV
     NLNVSYGQVL ELTSRATRVT KERDSALSKM SLWMKTCKQL EQEKEDLKSA LQQKKTEAEE
     LKAALDGRKK QLEEKNGELE EVKSELTELN NILEEKSREA DESMEKYCNL MVKVHKLEET
     NDALSTRLEQ LSASQHTNNN NGHSNSSDEN MTPLTPLIPL KSPQGSSSGK RGHRDISDKD
     GAQEALHNLT KKIKANAVTT PKARLEQEDE EFRPEGLPEL VQKGFADIPL GEASPFIIRR
     TTVKRCSPRL AARQFAPTSA PDGRVSSYNH LTHAVNIRKC LSPSGEDKPT SQFLNKGRTP
     EQREEQQGDN CHVQ
//
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