ID A0A3Q4AC30_MOLML Unreviewed; 2354 AA.
AC A0A3Q4AC30;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 10-FEB-2021, entry version 11.
DE SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSMMOP00000001510};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000001510, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000001510}
RP NUCLEOTIDE SEQUENCE.
RA Yu H., Pan H.;
RT "The genome of Mola mola.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSMMOP00000001510}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (JAN-2019) to UniProtKB.
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DR Ensembl; ENSMMOT00000001539; ENSMMOP00000001510; ENSMMOG00000001243.
DR GeneTree; ENSGT00730000111187; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR GO; GO:0060271; P:cilium assembly; IEA:Ensembl.
DR GO; GO:0001947; P:heart looping; IEA:Ensembl.
DR GO; GO:0001822; P:kidney development; IEA:Ensembl.
DR GO; GO:0021591; P:ventricular system development; IEA:Ensembl.
DR InterPro; IPR043513; Cenp-F.
DR InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR InterPro; IPR018463; Centromere_CenpF_N.
DR PANTHER; PTHR18874; PTHR18874; 2.
DR Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR Pfam; PF10473; CENP-F_leu_zip; 2.
DR Pfam; PF10481; CENP-F_N; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT DOMAIN 1..302
FT /note="CENP-F_N"
FT /evidence="ECO:0000259|Pfam:PF10481"
FT DOMAIN 1430..1547
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 1663..1792
FT /note="CENP-F_leu_zip"
FT /evidence="ECO:0000259|Pfam:PF10473"
FT DOMAIN 2244..2288
FT /note="CENP-F_C_Rb_bdg"
FT /evidence="ECO:0000259|Pfam:PF10490"
FT REGION 50..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2173..2217
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2231..2253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2319..2354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 275..330
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 428..536
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 551..634
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 655..682
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 687..735
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 747..767
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 783..869
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 881..908
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 947..981
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 986..1006
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1035..1065
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1070..1132
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1159..1371
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1392..1412
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1441..1482
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1511..1531
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1569..1596
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1639..1708
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1712..1790
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1812..1923
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1931..1986
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2070..2146
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 129..157
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..397
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2173..2210
FT /note="Polar"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2338..2354
FT /note="Polyampholyte"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2354 AA; 271664 MW; C2F0C7AC57741495 CRC64;
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERTQKQFQ LDSLEAALQK QKQKVSSERT
ETSAMKRENQ SLVESCDSLE KARQKVSHDL GVKEHMFEHN NILKLEWHSM LFLSSFHLLR
YKNELDRSQP AGCSSLSSSE LQPYTTPQKS FTTPAPAHRH QDNRLEELQE KYSQEIEERK
RLETELKVLQ VKLLTQSTAS VSHKDIAARQ GGSSIFPWQQ QDQAHSRQCQ DAMETPLKRR
GTSLWEAHEE TPLKINQRMS CPRALQSPSG SSQQMEQLKT INQELRGRVS ELERNLSSHE
KEIRSQTSKL QELQIQLNQA RKELTDRDKD LVKIRHETHA NDKHFSYCLT EEMSCQRHNA
ESCRRALEQK LKEQERGSQK ELGQLQSSQQ ALEQQLNQTR TKLTQEIQQS KKDYNVLQAD
MEKMCFQKNQ MVKEVEEQKQ KLLRSEQNLQ AYQNKEQDLH KKMEELQKEK NIVVVQLDQS
SRRLSQLEEE KKSTDQSLKR TQGLLDDLKA KSEGQVEELK RLQSKLEQQT QASTQELLTI
KKKFSDVETK NDRSQIELQK QTQEAEKLTK SLSVLEKESQ ELKSNLTASL KECDELKKEH
QALLQWKNEK ESLVNEAEAV QKDLTDKIGN LEKSEKAKGD KASLSAHIDS LKGELLNKST
ELEEREHQYK ELQSKFSEAG QKHTKDLENV AVQVKQLEAK VKELELRLQK ESARADQAER
TNSELQDEHQ AACDLAHSKD QLLELGQAEI SQLRESLNQT IAQQEEQLNL VFMFQVSSMD
QCLKVQEHLA AELQKQIKKL SDDEKEHKKI NEKKSEEIRQ LEEELKDLQS HTEEKQKLLR
DTEAKVLFLE KEKNDLENTA KEAELYILQI VNLSFFFKTL QQTQTEKINN LLEQISSLDE
ELTASRDAAK KLTALKSELD MVNQSHADLK KCMENLERSH SSTIEIKASL ENLLTEKNNL
ISTLENEVKG LKEKMSNLSE THTLEMENVL NKEKHIKLQL DAAKQKVAAA KLESSSRREE
IKTMKTTLTA ASRGLEERDD TIESLKEKLN KAEMEQAKMS DLLKEKTVAM NKIKVQLEML
QMDLEDNETA MNSFDSQVEE LKGTIESLES QLAQNQTQMS DMEARLEESK AQVKPLSCMK
FFILEISLRQ IIGDKDKSIN QMLQDKNNLE TTLKQLLDNK EQVETEIIQV NAQRKELEAC
VAKLSEENKQ LQTTMKQLTE DKQKIDQITQ EKEEVELTLR QVNEQKAELD ITISQINQDK
TRLEAILNEL TTEKQNSAAR LNQVVEEKLQ LEAHCNQLIE ENTKLQCSLN QLTEEKLLLQ
KSIDRREGEV TSLKDENEVI QNALLSSEQE LQRLQEQLEM RDKRAEEEEN RERYKSSALH
SDKLLWVHFK FLAQLSEERE TLNLQLQTSK CQLADVMEML EGLEMAKGGW DEKFLQRESE
LKRVRSEKAN LEQHILGMES ELEILHEERT KLRDEVETQR KMGSGMEQQI QTLITETTQL
RSELVSCTEE RDDLSQSLGQ WRDKVQNLEK TNCDTRNLIS ILEDDIRAGG KEFATDSFPF
LHLKLLEQIK AMEQAISQQN GEREELIGQL DKITEDHTSA NQNTETMVGK IQALEGKVCC
LSQSLEASLL EKGEIASRLN STQEEVQQMR TGIEKLQVRI ESDERKKRKM AELLKAAQRK
FDSLQDRIDA LERERDDVEQ SLEEAVLQVF CCKHVEDEKR ELSDKLSELS ATLDNLRSEK
EWMERELETK NREIEELKAV KEENRVKELE KGMREEAERQ TRIMDDLQQQ LQASWQKALS
LEERSAETEG VRETMQTLLA EMEKERTCLQ TEGERLRCEA EEWEKERNNL RSSIEALKEE
IQDCKAYIKA EEEEKKNLLS TLSSVEQQRE NLQGDLVSVE GEKEKLEQES KVLAVEKEKL
QSSLSVIAKE HHDTQQTLSS LTQQNHRIEE EKQKLETEKE ALLSLLSAIE VEKNDLSSAL
SALEQEKMCL NPIISLVELH GPIESTDKNM YPKRVNFQMN QYATDRSDDD FLFKFISTWV
NLNVSYGQVL ELTSRATRVT KERDSALSKM SLWMKTCKQL EQEKEDLKSA LQQKKTEAEE
LKAALDGRKK QLEEKNGELE EVKSELTELN NILEEKSREA DESMEKYCNL MVKVHKLEET
NDALSTRLEQ LSASQHTNNN NGHSNSSDEN MTPLTPLIPL KSPQGSSSGK RGHRDISDKD
GAQEALHNLT KKIKANAVTT PKARLEQEDE EFRPEGLPEL VQKGFADIPL GEASPFIIRR
TTVKRCSPRL AARQFAPTSA PDGRVSSYNH LTHAVNIRKC LSPSGEDKPT SQFLNKGRTP
EQREEQQGDN CHVQ
//
