ID   A0A3Q4ASF8_MOLML        Unreviewed;       922 AA.
AC   A0A3Q4ASF8;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Chordin {ECO:0000256|ARBA:ARBA00016968};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000007520.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000007520.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the chordin family.
CC       {ECO:0000256|ARBA:ARBA00007156}.
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DR   AlphaFoldDB; A0A3Q4ASF8; -.
DR   STRING; 94237.ENSMMOP00000007520; -.
DR   Ensembl; ENSMMOT00000007662.1; ENSMMOP00000007520.1; ENSMMOG00000005852.1.
DR   OMA; CCKSCPG; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0009790; P:embryo development; IEA:UniProt.
DR   GO; GO:0007389; P:pattern specification process; IEA:UniProt.
DR   GO; GO:0048731; P:system development; IEA:UniProt.
DR   Gene3D; 6.20.200.20; -; 3.
DR   InterPro; IPR016353; Chordin.
DR   InterPro; IPR010895; CHRD.
DR   InterPro; IPR001007; VWF_dom.
DR   PANTHER; PTHR46526; CHORDIN; 1.
DR   PANTHER; PTHR46526:SF1; CHORDIN; 1.
DR   Pfam; PF07452; CHRD; 3.
DR   Pfam; PF00093; VWC; 4.
DR   PIRSF; PIRSF002496; Chordin; 1.
DR   SMART; SM00754; CHRD; 4.
DR   SMART; SM00214; VWC; 4.
DR   SUPFAM; SSF57603; FnI-like domain; 4.
DR   PROSITE; PS50933; CHRD; 4.
DR   PROSITE; PS01208; VWFC_1; 2.
DR   PROSITE; PS50184; VWFC_2; 4.
PE   3: Inferred from homology;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473, ECO:0000256|PROSITE-
KW   ProRule:PRU00230}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..922
FT                   /note="Chordin"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5018759854"
FT   DOMAIN          42..118
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          155..270
FT                   /note="CHRD"
FT                   /evidence="ECO:0000259|PROSITE:PS50933"
FT   DOMAIN          272..386
FT                   /note="CHRD"
FT                   /evidence="ECO:0000259|PROSITE:PS50933"
FT   DOMAIN          387..510
FT                   /note="CHRD"
FT                   /evidence="ECO:0000259|PROSITE:PS50933"
FT   DOMAIN          516..643
FT                   /note="CHRD"
FT                   /evidence="ECO:0000259|PROSITE:PS50933"
FT   DOMAIN          673..732
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          751..820
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          840..904
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
SQ   SEQUENCE   922 AA;  103181 MW;  24529C98BA3F8B37 CRC64;
     MLRSLLCALS CAWLHAGAGS RLKSAALPIQ SEREPLPSKG LSGCSFGSRF YSLEDTWHPD
     LGEPFGVMHC VQCYCEPQKS HRGKVFGKVN CKNIKQDCPD LDCDDPVLLP GRCCKTCPRG
     EHLPTKACKE KEDDLHKSYN DRSYLSSEEV GSEESRTDFV AVLTGVTDSW LPSSSGVARA
     RFSLTKTSLA FSITYQRMDR PSKIAFLDSD GTAAFEFRVP RGQSDMICGV WKNLAKPLMR
     QLQSEQLRIS VSTSTSRREE VEGKIIKHRA LFAETFSSTL TSDEQNSGMG GIALLTLSDT
     ENNLHFILIL QGLPVLMPIR VQLVYRQHVL REIRANITSH DPDFAEVLTD LNSRELFWLS
     RGQLEITVAT EGQEPRQISG FITGRKSCDT IQSVMSSGDA LTPGKTGGVG SAIFNLHDNG
     TLDYQVQVAG LTSDFVGLTI ELKPRRRNKR SILYDLTPEY KRATGRAQGS WSRLEARHIH
     MLLQNELFVN VATAHNQEGE LRGQIKALFY NGLEAHRHEL PVPLAGQFVS PPVRTAASGH
     AWVSVDKQCH LHYEIIVAGL SKADDLTVNA HLHGLAEIGE IDDSSNVHRR LLTGFYGSQA
     QGVLKDISVE LLRHLDRGTA FIQVSTKMNP RGEIRGQVHV PNTCEFGTRG ETDEAEFDDF
     FVKDPEELKK DPHTCFFENQ HRAHGSRWTP NYDKCFSCSC QKRTVICDPV ICPVLTCSRT
     IQPGDKCCPI CDERKDPKDM KAPERVDEHL EGCYFEGDQK MHAPGTTWHP FVPPFGYIKC
     AVCTCKGSSG EVHCEKVTCP VLSCSHPVRR NPSDCCKECP EEEKTAGLEH SDMMQADGPR
     HCKFGKNYYQ NSDNWHPWVP LVGEMKCINC WCDHGVTKCQ RKQCPVLTCS NITRREGSCC
     PDCLEEDELT MKAPNRRQSW RH
//