ID   A0A3Q4AZN5_MOLML        Unreviewed;       586 AA.
AC   A0A3Q4AZN5;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000010450.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000010450.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the rad17/RAD24 family.
CC       {ECO:0000256|ARBA:ARBA00006168}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; A0A3Q4AZN5; -.
DR   Ensembl; ENSMMOT00000010633.1; ENSMMOP00000010450.1; ENSMMOG00000008056.1.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR004582; Checkpoint_prot_Rad17_Rad24.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR12172; CELL CYCLE CHECKPOINT PROTEIN RAD17; 1.
DR   PANTHER; PTHR12172:SF0; CELL CYCLE CHECKPOINT PROTEIN RAD17; 1.
DR   Pfam; PF03215; Rad17; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          79..230
FT                   /note="AAA+ ATPase"
FT                   /evidence="ECO:0000259|SMART:SM00382"
FT   REGION          300..323
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          534..575
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        536..550
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..572
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   586 AA;  65833 MW;  727AB1FDDA3D21B6 CRC64;
     SQSEKRNGSQ ALCFNANSKR ARKRKVEKAK VGCSDQHTSY LLKDSALRDQ DDEPWVDRYS
     PRSQVSLITF YFPACCHLQG GILLLTGPSG CGKTATVQVL AQELGLRIQE WTNPTNLDEL
     FLRTYTTILW MNGLSCSSQF AQFQDFLLRA NKYNCLKMVG DGGATEKKLI LVEDFPNQFY
     RQPGNLHDIL RHFVKTSRCP LVFIVSDSLS GDGSLRFLFP RDIQEELDIS NISFNPVAPT
     TMLKVLTRIS TLEAGKSCGR VPISDQTVLE TLCSGSSGDI RSAINSLQFF SLPEKGLWRM
     RKDRPASRTS RTKKSKQTKQ LEDEHAFGGK DASLFLFRAL GKILHCKREC ASGPGLPPHL
     SHHYRNMLLV NPELVVERSH MSGEFFILYL HQNYLDFFSE VEDVDHASEY LSDADLLSAD
     WMNRSTMGDY GSSVATRGLL FSNSQQVSVG FRPLHKPNWL LVNKNENCLA AQSLFRSFCM
     MPVSLQTELL PYLAKLTNPM RNHGNIHIRT LFVTIGLCAV SRLKLETLSD KEPGLLEVDP
     EEEDVEENKE GQGGVEEGLP SSQPQPNSSQ VLLEGEELII EQYDSD
//