ID A0A3Q4BIY8_MOLML Unreviewed; 555 AA.
AC A0A3Q4BIY8;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Integrator complex subunit 11 {ECO:0000256|ARBA:ARBA00016810};
DE AltName: Full=Cleavage and polyadenylation-specific factor 3-like protein {ECO:0000256|ARBA:ARBA00029625};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000019817.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000019817.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. RNA-
CC metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
CC {ECO:0000256|ARBA:ARBA00007093}.
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DR AlphaFoldDB; A0A3Q4BIY8; -.
DR STRING; 94237.ENSMMOP00000019817; -.
DR Ensembl; ENSMMOT00000020150.1; ENSMMOP00000019817.1; ENSMMOG00000015040.1.
DR OMA; YLDGMIW; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR CDD; cd16291; INTS11-like_MBL-fold; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR041897; INTS11-like_MBL-fold.
DR InterPro; IPR048662; IntS11_C.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF21386; IntS11_C; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT DOMAIN 16..206
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 233..320
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 555 AA; 62561 MW; 2EB0551CD0577323 CRC64;
MPEIKVTPLG AGQDVGRSCI LVSIGGKNIM LDCGMHMGYN DDRRFPDFSY VTQNGRLTDF
LDCVIISHFH LDHCGALPYM SEMVGYDGPI YMTHPTKAIC PILLEDFRKI TVDKKGETNF
FTSQMIKDCM KKVVPLNLHQ TVQVDDELEI KAYYAGHVLG AAMVNIKVGS ESVVYTVSAN
TPARAAWIDK CRPDILISES TYATTIRDSK RCRERDFLKK VHESIERGGK VRVQERMNLK
APIYFSTGLT EKANHYYKLF ITWTNQKIRK TFVQRNMFEF KHIKAFDRSY ADNPGPMVSL
FLCKVIMPGY CVQGTIGHKI LNGQRKLEME GRATLDVKLQ VEYMSFSAHA DAKGIMQLIR
MAEPRNMLLV HGEAAKMEFL KGKIEQEFSI DCYMPANGET TTVTTNPSVP VDISLNLLKR
EMALGGTLPD PKKPRAMHGT LIMKENLVSS EQALKELGLN EHQLRFTCRV QLQDPHSDSD
TLHRIYTHLK SVLKGYTIQH LPDGTVMVES IVIKVSSSAE DSNNKVLLLS WSYQDEDLGS
YLSNLLKKGL PPGVC
//
