ID   A0A3Q4BLC7_MOLML        Unreviewed;       153 AA.
AC   A0A3Q4BLC7;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=Mitochondrial inner membrane protease subunit {ECO:0000256|RuleBase:RU362041};
DE            EC=3.4.21.- {ECO:0000256|RuleBase:RU362041};
OS   Mola mola (Ocean sunfish) (Tetraodon mola).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Eupercaria; Tetraodontiformes; Molidae; Mola.
OX   NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000021037.1, ECO:0000313|Proteomes:UP000261620};
RN   [1] {ECO:0000313|Ensembl:ENSMMOP00000021037.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBUNIT: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
CC       {ECO:0000256|ARBA:ARBA00011805}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC       Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273,
CC       ECO:0000256|RuleBase:RU362041}.
CC   -!- SIMILARITY: Belongs to the peptidase S26 family. IMP1 subfamily.
CC       {ECO:0000256|ARBA:ARBA00038445}.
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DR   AlphaFoldDB; A0A3Q4BLC7; -.
DR   STRING; 94237.ENSMMOP00000021037; -.
DR   Ensembl; ENSMMOT00000021393.1; ENSMMOP00000021037.1; ENSMMOG00000015996.1.
DR   OMA; CKGPSME; -.
DR   Proteomes; UP000261620; Unplaced.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR   CDD; cd06530; S26_SPase_I; 1.
DR   Gene3D; 2.10.109.10; Umud Fragment, subunit A; 1.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR000223; Pept_S26A_signal_pept_1.
DR   InterPro; IPR019533; Peptidase_S26.
DR   NCBIfam; TIGR02227; sigpep_I_bact; 1.
DR   PANTHER; PTHR12383:SF16; MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1; 1.
DR   PANTHER; PTHR12383; PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED; 1.
DR   Pfam; PF10502; Peptidase_S26; 2.
DR   PRINTS; PR00727; LEADERPTASE.
DR   SUPFAM; SSF51306; LexA/Signal peptidase; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU362041};
KW   Membrane {ECO:0000256|RuleBase:RU362041};
KW   Mitochondrion {ECO:0000256|RuleBase:RU362041};
KW   Mitochondrion inner membrane {ECO:0000256|RuleBase:RU362041};
KW   Protease {ECO:0000256|RuleBase:RU362041};
KW   Reference proteome {ECO:0000313|Proteomes:UP000261620}.
FT   DOMAIN          19..96
FT                   /note="Peptidase S26"
FT                   /evidence="ECO:0000259|Pfam:PF10502"
FT   DOMAIN          102..143
FT                   /note="Peptidase S26"
FT                   /evidence="ECO:0000259|Pfam:PF10502"
FT   ACT_SITE        40
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600223-1"
FT   ACT_SITE        83
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600223-1"
SQ   SEQUENCE   153 AA;  16993 MW;  42E45C7398998BC8 CRC64;
     MLRRVLGRTL GFVGYAVQYG CIAHCAFEYI GEVVVCSGPS MEPTIVSHDI VFSERMSRHL
     YRIQKGDIVI AKSPLDPNMN ICKRVIGLEG DKVCSRGPSD LFKSHTYVPK GHVWLEGDNL
     RNSSDSRSYG PVPYALIRGR VCLKVTGGVL MLY
//