ID A0A3Q4BV74_MOLML Unreviewed; 854 AA.
AC A0A3Q4BV74;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSMMOP00000025732.1};
OS Mola mola (Ocean sunfish) (Tetraodon mola).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Tetraodontiformes; Molidae; Mola.
OX NCBI_TaxID=94237 {ECO:0000313|Ensembl:ENSMMOP00000025732.1, ECO:0000313|Proteomes:UP000261620};
RN [1] {ECO:0000313|Ensembl:ENSMMOP00000025732.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
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DR AlphaFoldDB; A0A3Q4BV74; -.
DR STRING; 94237.ENSMMOP00000025732; -.
DR Ensembl; ENSMMOT00000026170.1; ENSMMOP00000025732.1; ENSMMOG00000019504.1.
DR OMA; PAWDYTL; -.
DR Proteomes; UP000261620; Unplaced.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR CDD; cd08666; APC10-HECTD3; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.30.2410.10; Hect, E3 ligase catalytic domain; 1.
DR Gene3D; 3.90.1750.10; Hect, E3 ligase catalytic domains; 1.
DR InterPro; IPR004939; APC_su10/DOC_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR042469; HECTD3.
DR PANTHER; PTHR46654; E3 UBIQUITIN-PROTEIN LIGASE HECTD3; 1.
DR PANTHER; PTHR46654:SF1; E3 UBIQUITIN-PROTEIN LIGASE HECTD3; 1.
DR Pfam; PF03256; ANAPC10; 1.
DR Pfam; PF00632; HECT; 1.
DR SMART; SM01337; APC10; 1.
DR SMART; SM00119; HECTc; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR PROSITE; PS51284; DOC; 1.
DR PROSITE; PS50237; HECT; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261620};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT TRANSMEM 801..826
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 212..389
FT /note="DOC"
FT /evidence="ECO:0000259|PROSITE:PS51284"
FT DOMAIN 504..790
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
SQ SEQUENCE 854 AA; 97228 MW; 976327F7B49609BD CRC64;
MSVDDNPHVL LGRIRFLNRC IESFKKSEPV PESLCYVPKE VCFKICKDSS STSSASSGPS
AGGSIAGKTL ISVFENPHQT PHMKKLCKYN IEPKKGTCIR TTGEEYRNSQ GLWVKITKEQ
MEEHRPGMEL EEGWILVCKH TEGGDRLVPV ESPETASRQQ QLFGYDHKPC NSWEQVVNME
NALYIGSKPK IAESDDTAVQ KLRYVPPTWN YECDEDLVHY FYDHIGKEDE NLGSVKQCVT
SIDVSSYSVM SCLTDGDTET YWESDGMQGQ HWIRLHMKRG SVVNKLILTV DSTDDNYMPK
RVTVFGGEGD NLKKLSDVTI DDNLIGEVCV LEDMTSHLPV IEIRIEECRD EGIDVRIRGL
KIKSSCERDL GLNADVFQSS NLVRYPRLHG NTPDVLYRRA LVIQRFIGLL DSVLPHLVPA
WDYSLGTFNQ IKSIKQFLLL SKRRSALITQ CLKDSETSKP NFMPRLYINR RLAMEHRDNP
SLDPSCKNAV LNQVFEGLKP SDKSEKTLDY RWPARYDQWW ECKFIAEGII DQGGGFRDSL
ADMSEELCPS SAECPMPLPF FCRTSNQGAL EARDYYVPNP SCKEFHKYEW IGQLMGAALR
GKDFLVLALP GLVWKQLTGE AVSWSKDFPA VDSVLVNLLE AMENMDQETF EFRFGEDLVY
TTLLSDGQIV ELIPSGSNMA VRYDDRSEFI RLVQKTRLEE SKQQIAAMQA GLLKVVPQAV
LDLLTWQEVE KKVCGDPEIS VEALKRLTHY EDLEQSNVRV QYLWEALTNF TNEDRSRFLR
FVTGRSRLPA PIYIFPDKQG VLIYVLLLGN ITYNAMSFLL FSILSCSAKV CEEKLRYAAY
NCVAIDTDMS PWEE
//
