ID   A0A3Q4FXA0_NEOBR        Unreviewed;       332 AA.
AC   A0A3Q4FXA0;
DT   10-APR-2019, integrated into UniProtKB/TrEMBL.
DT   10-APR-2019, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Acyl-coenzyme A thioesterase 5-like {ECO:0000313|Ensembl:ENSNBRP00000000216.1};
OS   Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC   Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX   NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000000216.1, ECO:0000313|Proteomes:UP000261580};
RN   [1] {ECO:0000313|Ensembl:ENSNBRP00000000216.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the C/M/P thioester hydrolase family.
CC       {ECO:0000256|ARBA:ARBA00006538}.
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DR   AlphaFoldDB; A0A3Q4FXA0; -.
DR   Ensembl; ENSNBRT00000000251.1; ENSNBRP00000000216.1; ENSNBRG00000000201.1.
DR   GeneTree; ENSGT01010000222336; -.
DR   Proteomes; UP000261580; Unplaced.
DR   Bgee; ENSNBRG00000000201; Expressed in liver and 9 other cell types or tissues.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.40.2240; Acyl-CoA thioester hydrolase/BAAT N-terminal domain; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR016662; Acyl-CoA_thioEstase_long-chain.
DR   InterPro; IPR014940; BAAT_C.
DR   InterPro; IPR006862; Thio_Ohase/aa_AcTrfase.
DR   InterPro; IPR042490; Thio_Ohase/BAAT_N.
DR   PANTHER; PTHR10824:SF17; ACYL-COENZYME A THIOESTERASE 6; 1.
DR   PANTHER; PTHR10824; ACYL-COENZYME A THIOESTERASE-RELATED; 1.
DR   Pfam; PF08840; BAAT_C; 1.
DR   Pfam; PF04775; Bile_Hydr_Trans; 1.
DR   PIRSF; PIRSF016521; Acyl-CoA_hydro; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT   DOMAIN          1..62
FT                   /note="Acyl-CoA thioester hydrolase/bile acid-CoA amino
FT                   acid N-acetyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF04775"
FT   DOMAIN          124..329
FT                   /note="BAAT/Acyl-CoA thioester hydrolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08840"
FT   ACT_SITE        149
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        244
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
FT   ACT_SITE        278
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR016521-1"
SQ   SEQUENCE   332 AA;  37002 MW;  EADE186B8EA2E004 CRC64;
     MGLLWSMTPD SLHKRLQKIN ALNPFMVKFS VHEETGEGRI LAEATNERIL MGDGVIRVPV
     KEGNIRGVLF TPPGRGPFPS VLDLYTYGGG LSEKRASLLA SRGFLVLTVA LYGHDDLPKN
     VKEIHLDYLE EAVEFLKKQT KVIGVISLSK SGDLALSVAS YLPDVEATVW INGCSANVVL
     PFYYKKRQIH SALMFDLKKA IPTESGAFIT KYVLNNPLAE ENKGSLIPIE QAKGHFLFVA
     SEDDLCWDSK AYMDQMVERL KRHGKEKFES VSYPGAGHYL EPPYGPYCRS SFNVVLGKPA
     LWGGEPKSHA AAEVHMWKKI QDFLRNHLIG KI
//