ID A0A3Q4FYH3_NEOBR Unreviewed; 442 AA.
AC A0A3Q4FYH3;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0000259|PROSITE:PS50262};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000000771.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000000771.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the chemokine-like receptor (CMKLR) family.
CC {ECO:0000256|ARBA:ARBA00025736}.
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DR AlphaFoldDB; A0A3Q4FYH3; -.
DR STRING; 32507.ENSNBRP00000000771; -.
DR Ensembl; ENSNBRT00000000818.1; ENSNBRP00000000771.1; ENSNBRG00000000672.1.
DR GeneTree; ENSGT01100000263564; -.
DR OMA; KISITHM; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000000672; Expressed in mesonephros.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004875; F:complement receptor activity; IEA:InterPro.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0006935; P:chemotaxis; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR002234; Anphylx_rcpt_C3a/C5a1-2.
DR InterPro; IPR000826; Formyl_rcpt-rel.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24225:SF56; C5A ANAPHYLATOXIN CHEMOTACTIC RECEPTOR 1; 1.
DR PANTHER; PTHR24225; CHEMOTACTIC RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 2.
DR PRINTS; PR01104; ANPHYLATOXNR.
DR PRINTS; PR00426; C5ANPHYLTXNR.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 2.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..128
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..318
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 338..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 50..397
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
SQ SEQUENCE 442 AA; 50089 MW; 012F63A0A5B736F7 CRC64;
MDYFSDYNYT FPDDNFTFPD IIESVTPEIK PIQIVALVMY SLVVLLGVPG NAVVVWVTGF
CMSRSVTSLW FLNLALADLL CCLSIPLLMV PLVHDDHWHF GPLACMLIRG LFYLVMYCSI
LQLVVISVDR LLLVIRPIWC QNHRRPKQGA YGCVAVWVLA LIGSIPQFVY AQEIEAGDEK
RECRMEYTVD SAWPVSAFRF LIGFIIPFLV ILVCHLVVFS KTQRRMTRGR TRSKKTLRVI
IAVVLIITIG TDSISISSAN TQTVCVLFVS QCVEIKAGDE KRECRMEYTV DSAWPVSAFR
FLIGFIIPFL VILVCHLVVF SNTQRRMTRG RTGSKKTLGV VIAMVLSFFL CWIPLHIVDF
LIMTTPQGSY VSPKLHLAHV IALFLAYINS CLNPLLYVCL GQSFKDSMNR SLRNILHFIS
ENMTTKISIT HMDSKNQNTD VT
//
