ID A0A3Q4G5X1_NEOBR Unreviewed; 373 AA.
AC A0A3Q4G5X1;
DT 10-APR-2019, integrated into UniProtKB/TrEMBL.
DT 10-APR-2019, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Hepatic leukemia factor-like {ECO:0000313|Ensembl:ENSNBRP00000003716.1};
OS Neolamprologus brichardi (Fairy cichlid) (Lamprologus brichardi).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids;
OC Pseudocrenilabrinae; Lamprologini; Neolamprologus.
OX NCBI_TaxID=32507 {ECO:0000313|Ensembl:ENSNBRP00000003716.1, ECO:0000313|Proteomes:UP000261580};
RN [1] {ECO:0000313|Ensembl:ENSNBRP00000003716.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family. PAR subfamily.
CC {ECO:0000256|ARBA:ARBA00009208}.
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DR RefSeq; XP_006803013.1; XM_006802950.1.
DR AlphaFoldDB; A0A3Q4G5X1; -.
DR STRING; 32507.ENSNBRP00000003716; -.
DR Ensembl; ENSNBRT00000003842.1; ENSNBRP00000003716.1; ENSNBRG00000002981.1.
DR GeneID; 102784192; -.
DR CTD; 569109; -.
DR GeneTree; ENSGT00940000165399; -.
DR OMA; HRLKNPC; -.
DR OrthoDB; 5354784at2759; -.
DR Proteomes; UP000261580; Unplaced.
DR Bgee; ENSNBRG00000002981; Expressed in blood and 6 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14695; bZIP_HLF; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR040223; PAR_bZIP.
DR PANTHER; PTHR11988:SF7; D SITE-BINDING PROTEIN; 1.
DR PANTHER; PTHR11988; THYROTROPH EMBRYONIC FACTOR RELATED; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000261580}.
FT DOMAIN 303..366
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 1..37
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 263..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 335..369
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..187
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..241
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 373 AA; 40382 MW; B8762A55C146C530 CRC64;
MSRQLSQLPT PDLPAGASPQ FGSCTQPGGS LTGGHLNSMA GLKSLLQHPM KGDQRLKNPC
DSKDKDRLDL DEDSLGVCPM RNGSGIVNSN SSNGCGGGGN GGGNFNQFLG PLLWDRTVPA
DGGLFQLQYM DLEEFLTENG MGSMHNNNNN NSSCSAQIPS QSPQSAVPNQ SSQCLPPPSP
PGSSSSPPST SSSPSLIGLE VAQPQNLPGG TDCLHGSQRR MNDSCESPSS SSSSSCPPLL
TPTGNGPDVI GMFDMDSSDM AMSNTSEEQN FDPRRHSFSE DELKPQPMIK KARKILVPDN
MKDEKYWTRR HKNNEAAKRS RDARRLKENQ ISVRAAYLER ENAALRQEVA EMRKELGRCR
NILSKYENRL ADQ
//
